Publications

Encouraging results for a new mesothelioma chemotherapy

Posted in Publications Published by Zoe Leech 12 April 2017

Other hard-to-treat cancers are now being tested

Encouraging results for a new mesothelioma chemotherapy

A new publication from Dr Peter Szlosarek and his team in the Journal of Clinical Oncology marks the next step in the development of a revolutionary treatment for mesothelioma.

This cancer of the lung lining is hard to treat and an increasing problem as more people develop the condition...

BCI successes at NCRI 2016

Posted in Conferences, In the Press, Publications Published by Zoe Leech 04 November 2016

New research coverage and poster prizes for Barts researchers

BCI successes at NCRI 2016

Congratulations to this year's poster prize winning PhD students, Lei Xu and Viola Walther, and to Dr Yong-Jie Lu for publishing their latest research on monitoring for prostate cancer spread using new blood test technology.

Read more about this year's conference...

Predicting cancer progression from Barrett’s Oesophagus

Posted in Publications Published by Zoe Leech 19 August 2016

Predicting cancer progression from Barrett’s Oesophagus

A new study from Dr Trevor Graham’s research group has been published in Nature Communications, led by postdoctoral researcher Dr Pierre Martinez. The results should improve monitoring and treatment for people with Barrett's oesophagus who are concerned about their risk of developing cancer...

Tactics to overcome mesothelioma treatment resistance

Posted in Publications Published by Zoe Leech 26 July 2016

Tactics to overcome mesothelioma treatment resistance

Pioneering work in our labs has led to a new "starvation" treatment strategy for mesothelioma, previously almost untreatable due to the difficulty of performing effective surgery and lack of available drugs.

Dr Sarah Martin has published new work on how mesothelioma could get around the attack with a view to preventing resistance and killing the cancer more efficiently...

Improving transplant therapy through "reverse translation" studies

Posted in Charity, Publications Published by Zoe Leech 01 July 2016

Two new publications made possible by the BCI Charity

Improving transplant therapy through

Two papers have been published by Dr Jeff Davies’ group focusing on the role of immunology in bone marrow transplant, a common and effective treatment for many types of blood cancer.

Both papers are examples of taking a clinical problem into the laboratory to find out why it’s happening and how we might go about fixing it. The second won our Paper of the Month competition in April 2016...

Cancer cells "talking to themselves" could be key to cancer spreading

Posted in BCI Spotlight Articles, Images, In the Press, Publications Published by Zoe Leech 23 June 2016

Newly discovered cell signalling platform could enable metastasis

Cancer cells

A key question in cancer research has been how cancer cells are able to survive once they break away from a tumour to spread around the body.

This publication from the Kermorgant lab showing a previously unknown signalling pathway from integrin beta-1 and c-Met could be key to cancer cell survival in metastasis...

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Posted in In the Press, Publications Published by Zoe Leech 15 June 2016

New study published in Clinical Cancer Research by Prof Balkwill

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Professor Fran Balkwill has published a study on ovarian cancer responses to treatment, which could mean hope for patients whose cancer has already spread.

The findings suggest that giving chemotherapy before surgery could improve tumour responses to immunotherapy given afterwards, by making the cancer cells more susceptible to immune attack by the immune system...

Vitamin A could boost pancreatic cancer chemotherapy

Posted in In the Press, Publications Published by Zoe Leech 25 May 2016

Vitamin A could boost pancreatic cancer chemotherapy

The latest study from the Kocher lab, published recently in the Journal of Pathology, has found that adding high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer.

This finding is now being taken forward in the clinical trial, STARPAC, by our Centre for Experimental Cancer Medicine.

Repurposing viruses to tackle pancreatic cancer drug resistance

Posted in Publications Published by Zoe Leech 15 April 2016

Repurposing viruses to tackle pancreatic cancer drug resistance

A new paper in the journal Oncotarget, led by Dr Gunnel Hallden, shows that viruses can be modified to force cancer cells to die, instead of evading apoptosis.

This also means they work better with existing anti-cancer drugs to destroy pancreatic tumours, a promising beginning to exploring more combination therapies to tackle the problem of drug resistance in pancreatic cancer...

Cancer evolution follows natural law - using maths to predict progression

Posted in Publications Published by Zoe Leech 19 January 2016

Cancer evolution follows natural law - using maths to predict progression

Dr Trevor Graham from our Centre for Tumour Biology has co-authored a new study in Nature Genetics, revealing new insights about evolutionary patterns of certain tumours.

This understanding could help us to predict tumour growth for some types of cancer and advance personalised medicine...

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