Articles tagged with: Microenvironment

Cancer cells "talking to themselves" could be key to cancer spreading

Posted in BCI Spotlight Articles, Images, In the Press, Publications Published by Zoe Leech 23 June 2016

Newly discovered cell signalling platform could enable metastasis

Cancer cells

A key question in cancer research has been how cancer cells are able to survive once they break away from a tumour to spread around the body.

This publication from the Kermorgant lab showing a previously unknown signalling pathway from integrin beta-1 and c-Met could be key to cancer cell survival in metastasis...

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Posted in In the Press, Publications Published by Zoe Leech 15 June 2016

New study published in Clinical Cancer Research by Prof Balkwill

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Professor Fran Balkwill has published a study on ovarian cancer responses to treatment, which could mean hope for patients whose cancer has already spread.

The findings suggest that giving chemotherapy before surgery could improve tumour responses to immunotherapy given afterwards, by making the cancer cells more susceptible to immune attack by the immune system...

Dr Susana Godinho awarded the prestigious Lister Prize – a first for QMUL

Posted in Grants & Awards Published by Zoe Leech 01 June 2016

Dr Susana Godinho awarded the prestigious Lister Prize – a first for QMUL

Dr Susana Godinho in our Centre for Molecular Oncology has become the first lecturer at BCI - and Queen Mary University of London as a whole - to be awarded the prestigious Lister Prize Fellowship.

Just five excellent researchers receive this award each year...

Vitamin A could boost pancreatic cancer chemotherapy

Posted in In the Press, Publications Published by Zoe Leech 25 May 2016

Vitamin A could boost pancreatic cancer chemotherapy

The latest study from the Kocher lab, published recently in the Journal of Pathology, has found that adding high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer.

This finding is now being taken forward in the clinical trial, STARPAC, by our Centre for Experimental Cancer Medicine.

BCI success in Academy of Medical Sciences grant awards

Posted in Grants & Awards Published by Zoe Leech 13 May 2016

BCI success in Academy of Medical Sciences grant awards

Three researchers from Queen Mary University of London (QMUL) have been awarded £100,000 each by the Academy of Medical Sciences. Two are here at BCI: Dr Paulo Ribeiro and Dr Angus Cameron.

The grants are designed to support researchers in the first years of their independent career with funds, training and mentoring. Angus' grant is for the study of cancer-associated fibroblasts (CAFs) while Paulo’s grant will fund a project studying tissue growth mechanisms...

Funding secured to revolutionise personalised prostate cancer treatments

Posted in Grants & Awards Published by Zoe Leech 23 November 2015

3D tumour model to test anti-cancer viruses & drugs

Funding secured to revolutionise personalised prostate cancer treatments

Barts Charity have funded a new project led by Dr Gunnel Halldén in our Centre for Molecular Oncology. This work aims to develop a method to test new combinations of cancer treatments on prostate cancer.

Ultimately they hope to use the test for individual patients, to provide personalised therapies...

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Posted in Publications Published by Zoe Leech 14 July 2015

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Two new papers from our Centre for Haemato-Oncology in the journal Blood show that boosting the immune system could help control Chronic Lymphocytic Leukaemia (CLL).

The studies focus on two proteins called “Programmed Death Ligand 1” (PD-L1) and Programmed Death 1” (PD-1), found on the surface of tumour and immune cells respectively...

Targeting blood vessels to sensitise tumours to therapy - new funding

Posted in Grants & Awards Published by Zoe Leech 07 July 2015

Targeting blood vessels to sensitise tumours to therapy - new funding

Professor Kairbaan Hodivala-Dilke has been awarded a new £2.3 million grant from Cancer Research UK to investigate the role of tumour blood vessels in how solid cancer responds to treatment.

This follows the group's recent publication exploring vascular promotion therapy as a potential combination cancer therapy...

Bennett Fellowship: hunting hidden leukaemia cells

Posted in Grants & Awards Published by Zoe Leech 16 April 2015

Bennett Fellowship: hunting hidden leukaemia cells

Dr Bela Wrench in our Centre for Haemato-Oncology has been awarded a Senior Clinical Researcher Bennett Fellowship by Leukaemia & Lymphoma Research.

She aims to tackle the problem of resistance in adult ALL due to tumour cell dormancy allowing cancer cells to escape treatment...

MRC grant funding success for BCI researchers

Posted in Grants & Awards Published by Zoe Leech 16 March 2015

MRC grant funding success for BCI researchers

Two new grants have been awarded to BCI researchers by the Medical Research Council (MRC).

Prof Hemant Kocher will now be able to run a Phase I trial for a new pancreatic cancer treatment, and Dr Yaohe Wang will be testing a modified cancer-killing (oncolytic) virus...

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