Centre for Tumour Biology
Led by Professor Sir Nicholas Wright
Our centre has 45 or more researchers, working on different aspects of the biology of transformed cells or the stromal cells found in neoplastic foci. We bring together individuals with a diverse range of expertise in cell biology, molecular biology and pathology to form a synergistic approach to complex biological problems.
Our unifying interest is in understanding the cellular and molecular events which drive tumour progression to the malignant phenotype. We have a particular interest in understanding the nature of the “cross-talk” between epithelial cancer cells and their stromal partners during cancer evolution.
The centre is based around an open-plan laboratory to maximise the opportunity for collaboration and interaction between the different groups and group members.
We bring together research scientists and clinicians to work on the research problems, with a focus always on the validation of ideas and observations in clinically-derived material, to ensure that bench-work is oriented toward understanding a “real” phenomenon.
Please click here for profiles of staff in the Centre for Tumour Biology
Life in the Centre
Follow the links below to get a sense of what life is like for researchers in our centre:
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Rachel Barrow |
Michael Allen |
Facilities
Here at the Centre for Tumour Biology we are responsible for the Zeiss 510 and the Zeiss 710 confocal microscopes, which are used in the imaging centre and greatly aid our work.
Major Projects
- February 2011 - February 2014. Medical Research Council Project Grant: £460,000 (Professor Kairbaan Hodivala-Dilke)
- October 2010 (duration 60 months). Modelling the stromal regulation of tumour angiogenesis. Cancer Research Programme Grant: £3.1M (Professor Kairbaan Hodivala-Dilke and Professor Louise Jones)
- Start 2010 (duration 60 months). Establishment of the BCC National Breast Tissue Bank, (joint with Leeds, Dundee and Nottingham) Breast Cancer Campaign. £3.5M total, £1.1M to Barts. (Professor Louise Jones)
