Our forerunner: the ICRF Medical Oncology Unit at Barts
The ICRF Medical Oncology Unit at St Bartholomew’s Hospital played a formative role in shaping modern cancer medicine in the UK. Established in 1970 under Professor Gordon Hamilton Fairley—the country’s first Professor of Medical Oncology—and Sir Ronald Bodley Scott, the Unit brought clinicians and scientists together to study cancer and test new treatments with patients.
- Professor Hamilton Fairley and Sir Ronald Bodley Scott introduced important drug combinations for blood cancers such as Hodgkin’s disease and acute myeloblastic leukaemia.
- Under Professor James Malpas, the Unit became an early leader in paediatric oncology, applying new approaches that combined several treatments (‘total therapy’) to improve outcomes for children with rare tumours.
- Professors Andrew Lister and Ama Rohatiner helped to pioneer high-dose chemotherapy supported by autologous stem cell rescue—a method that uses a patient’s own blood-forming cells to help them recover after intensive treatment.
- Dr Peter Wrigley, Dr Maurice Slevin and Dr Simon Joel carried out influential research into the way cancer drugs are processed by the body, shaping how medicines such as etoposide and morphine are used today.
The Unit was also notable for its collaborative culture, contributing to national clinical trial groups, and introducing coordinated multidisciplinary teamworking long before it became the norm. Its legacy continues through the Centre for Haemato-Oncology within the Barts Cancer Institute.