Publications

Study sheds new light on how cancer cells adapt to become aggressive

Posted in General News, Publications Published by Reza Roozitalab 04 December 2017

Centrosome amplification: not as clear cut as once thought

Study sheds new light on how cancer cells adapt to become aggressive

A new study from Dr Susana Godinho’s lab has revealed surprising insights into how cancer cells adapt to ‘centrosome amplification’ – a mechanism that they have previously demonstrated to be essential in allowing certain tumours to become aggressive and metastatic.

Epigenetic editing: not just a one 'hit' wonder

Posted in General News, Publications Published by Reza Roozitalab 13 November 2017

New research published today in Nature Communications

Epigenetic editing: not just a one 'hit' wonder

For the very first time, researchers at BCI have shown that modifying the ‘epigenome’ of a healthy breast cell is not only possible, but precise enough to initiate a chain reaction of events that make the cell abnormal.

A link between low oxygen "loving" microbes and prostate cancer?

Posted in General News, Publications Published by Reza Roozitalab 09 November 2017

New MALDI-TOF research suggests a link between prostate cancer and low "oxygen" loving bacteria

 A link between low oxygen

Research by Professor Tim Oliver brings to light a possible new link between microbes and prostate cancer, an association that may indicate a radical change in thinking about the causes of the disease.

A New Target Linked with Several Aggressive Forms of Blood Tumour

Posted in General News, Publications Published by Reza Roozitalab 23 October 2017

Lamin B1 - a potential target for follicular lymphoma and Chronic lymphocytic leukaemia

A New Target Linked with Several Aggressive Forms of Blood Tumour

Manipulating levels of Lamin B1 may one day prove an effective treatment option for patients with lymphomas and chronic lymphocytic leukaemia...

Blood cell identifies patients with aggressive prostate cancer

Posted in Publications Published by Zoe Leech 19 June 2017

Blood cell identifies patients with aggressive prostate cancer

Patients who have aggressive prostate cancer could be identified by a highly accurate and simple blood test, according to an early study by Queen Mary University of London (QMUL).

The research discovered rare cells in the blood that could be used to identify patients who are 10 times more likely to die of their prostate cancer, allowing targeted treatments to be offered as early as possible.

Encouraging results for a new mesothelioma chemotherapy

Posted in Publications Published by Zoe Leech 12 April 2017

Other hard-to-treat cancers are now being tested

Encouraging results for a new mesothelioma chemotherapy

A new publication from Dr Peter Szlosarek and his team in the Journal of Clinical Oncology marks the next step in the development of a revolutionary treatment for mesothelioma.

This cancer of the lung lining is hard to treat and an increasing problem as more people develop the condition...

BCI successes at NCRI 2016

Posted in Conferences, In the Press, Publications Published by Zoe Leech 04 November 2016

New research coverage and poster prizes for Barts researchers

BCI successes at NCRI 2016

Congratulations to this year's poster prize winning PhD students, Lei Xu and Viola Walther, and to Dr Yong-Jie Lu for publishing their latest research on monitoring for prostate cancer spread using new blood test technology.

Read more about this year's conference...

Predicting cancer progression from Barrett’s Oesophagus

Posted in Publications Published by Zoe Leech 19 August 2016

Predicting cancer progression from Barrett’s Oesophagus

A new study from Dr Trevor Graham’s research group has been published in Nature Communications, led by postdoctoral researcher Dr Pierre Martinez. The results should improve monitoring and treatment for people with Barrett's oesophagus who are concerned about their risk of developing cancer...

Tactics to overcome mesothelioma treatment resistance

Posted in Publications Published by Zoe Leech 26 July 2016

Tactics to overcome mesothelioma treatment resistance

Pioneering work in our labs has led to a new "starvation" treatment strategy for mesothelioma, previously almost untreatable due to the difficulty of performing effective surgery and lack of available drugs.

Dr Sarah Martin has published new work on how mesothelioma could get around the attack with a view to preventing resistance and killing the cancer more efficiently...

Improving transplant therapy through "reverse translation" studies

Posted in Charity, Publications Published by Zoe Leech 01 July 2016

Two new publications made possible by the BCI Charity

Improving transplant therapy through

Two papers have been published by Dr Jeff Davies’ group focusing on the role of immunology in bone marrow transplant, a common and effective treatment for many types of blood cancer.

Both papers are examples of taking a clinical problem into the laboratory to find out why it’s happening and how we might go about fixing it. The second won our Paper of the Month competition in April 2016...

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