Articles tagged with: Colorectal

Uncovering the evolutionary history of IBD-associated colorectal cancer

Posted in General News, Publications Published by Bethan Warman 11 July 2018

Uncovering the evolutionary history of IBD-associated colorectal cancer

A team of researchers from the BCI, led by Prof Trevor Graham, Lead of the Evolution and Cancer Biology Laboratory, have reported the genetic events involved in the early development of bowel cancer in patients with inflammatory bowel disease (IBD). Such knowledge may be able to be exploited to design simple diagnostic tests to stratify patients with IBD at high risk of developing cancer.

IBD more than doubles an individual’s lifetime risk of developing bowel cancer, and the risk increases significantly if they have suffered with IBD for a sustained period of time. With this in mind, the study published today in Gut- performed in collaboration with researchers from St Mark’s Hospital, led by Prof Ailsa Hart, and the University of Oxford, led by Prof Simon Leedham- set out to understand the genetics of how CRC develops in people with IBD.

Seema Jaswal visits the BCI

Posted in General News, Engagement Published by Bethan Warman 15 March 2018

Celebrating International Women's Day

Seema Jaswal visits the BCI

Last Thursday was International Women’s Day- a day that celebrates the social, political, cultural and economic achievements of women from all over the world. Recently, an inspirational woman, Seema Jaswal- a television and radio presenter- visited us here at the Barts Cancer Institute (BCI) to meet some of our researchers and find out more about the cutting edge research that goes on here.

Seema’s TV career began at Sky Sports where she worked as a Runner before receiving her first presenting job on CBBC Sports Round. Seema’s successful career has since seen her host a variety of events, including the Indian Super League, India’s FIFA U17 World Cup and the Premier League. Last year, Seema was named as one of We Are The City’s Inspirational Women.

Tracking treatment-resistant cells in bowel cancer

Posted in General News, Publications Published by Reza Roozitalab 02 January 2018

A powerful new tool for cancer research

Tracking treatment-resistant cells in bowel cancer

Scientists at the BCI have applied a new method to precisely map the location of potentially treatment-resistant mutant cells inside human tumours.

The new method, named BaseScope, allows researchers to see how cells that carry a particular genetic mutation are organised within a tumour. These ‘maps’ of mutant cancer cells (see picture) reveal new information about how tumours grow.

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