Articles tagged with: Genetics

BCI at the 59th ASH Annual Meeting

Posted in General News, Conferences, BCI on the Road Published by Reza Roozitalab 08 December 2017

"The most prestigious event in the haematology calendar"

BCI at the 59th ASH Annual Meeting

Research teams from our Centre for Haemato-Oncology have once again joined the world’s most influential figures in haematology to present their cutting-edge findings at the 59th ASH Annual Meeting & Exposition.

Study sheds new light on how cancer cells adapt to become aggressive

Posted in General News, Publications Published by Reza Roozitalab 04 December 2017

Centrosome amplification: not as clear cut as once thought

Study sheds new light on how cancer cells adapt to become aggressive

A new study from Dr Susana Godinho’s lab has revealed surprising insights into how cancer cells adapt to ‘centrosome amplification’ – a mechanism that they have previously demonstrated to be essential in allowing certain tumours to become aggressive and metastatic.

Epigenetic editing: not just a one 'hit' wonder

Posted in General News, Publications Published by Reza Roozitalab 13 November 2017

New research published today in Nature Communications

Epigenetic editing: not just a one 'hit' wonder

For the very first time, researchers at BCI have shown that modifying the ‘epigenome’ of a healthy breast cell is not only possible, but precise enough to initiate a chain reaction of events that make the cell abnormal.

A New Target Linked with Several Aggressive Forms of Blood Tumour

Posted in General News, Publications Published by Reza Roozitalab 23 October 2017

Lamin B1 - a potential target for follicular lymphoma and Chronic lymphocytic leukaemia

A New Target Linked with Several Aggressive Forms of Blood Tumour

Manipulating levels of Lamin B1 may one day prove an effective treatment option for patients with lymphomas and chronic lymphocytic leukaemia...

Introducing BCI Animations - blood cancers and solid tumours

Posted in General News, Engagement Published by Zoe Leech 13 March 2017

Haemato-Oncology and Tumour Biology

Introducing BCI Animations - blood cancers and solid tumours

BCI has been working with Phospho Biomedical Animations to bring some of our key cancer research topics to life.

Watch these short videos to learn about two of our research Centres' major experimental subjects. Let us know what you think!

BCI at the 58th ASH Annual Meeting

Posted in Conferences Published by Zoe Leech 06 January 2017

BCI at the 58th ASH Annual Meeting

Our Centre for Haemato-Oncology researchers travelled to the ASH convention centre in San Diego and, true to form, delivered several excellent presentations that won them an impressive array of prizes...

Predicting cancer progression from Barrett’s Oesophagus

Posted in Publications Published by Zoe Leech 19 August 2016

Predicting cancer progression from Barrett’s Oesophagus

A new study from Dr Trevor Graham’s research group has been published in Nature Communications, led by postdoctoral researcher Dr Pierre Martinez. The results should improve monitoring and treatment for people with Barrett's oesophagus who are concerned about their risk of developing cancer...

New grant to help predict oesophageal cancer risk

Posted in Grants & Awards Published by Zoe Leech 04 July 2016

Understanding the evolution of Barrett’s oesophagus

New grant to help predict oesophageal cancer risk

Dr Stuart McDonald will receive a programme foundation award of ~ £1.2 million from Cancer Research UK.

It will allow the group to study how the pre-cancerous condition Barrett’s oesophagus evolves into cancer through investigating genetic and structural changes in the tissue over time.

With this award the team also hopes to find novel biomarkers that can change how we look after patients with Barrett’s oesopahgus...

Improving transplant therapy through "reverse translation" studies

Posted in Charity, Publications Published by Zoe Leech 01 July 2016

Two new publications made possible by the BCI Charity

Improving transplant therapy through

Two papers have been published by Dr Jeff Davies’ group focusing on the role of immunology in bone marrow transplant, a common and effective treatment for many types of blood cancer.

Both papers are examples of taking a clinical problem into the laboratory to find out why it’s happening and how we might go about fixing it. The second won our Paper of the Month competition in April 2016...

BCI Postgraduate Day 2016 - Celebrating Student Achievements

Posted in Engagement, Events Published by Zoe Leech 17 June 2016

BCI Postgraduate Day 2016 - Celebrating Student Achievements

This year our annual Postgraduate Day was held on 14th June.

The event showcases our postgraduate students' work at BCI, also giving them practice for national and international meetings, as well as encouraging them to form their research plans...

 

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