Articles tagged with: Integrins

Hugh Brasher and Pancreatic Cancer UK Visit the BCI

Posted in General News, Engagement Published by Reza Roozitalab 10 November 2017

November is Pancreatic Cancer Awareness Month #PCAM

Hugh Brasher and Pancreatic Cancer UK Visit the BCI

Hugh Brasher and members of the team from Pancreatic Cancer UK visited the BCI to learn about the latest research and what is being done to beat pancreatic cancer sooner.

New PCRF grants and Industrial CASE studentship awarded

Posted in Grants & Awards Published by Zoe Leech 18 January 2017

New PCRF grants and Industrial CASE studentship awarded

Three of our researchers in the Centres for Tumour Biology and Molecular Oncology have recently won awards allowing them to begin and continue research projects in pancreatic cancer and make headway in finding new treatments...

Cancer cells "talking to themselves" could be key to cancer spreading

Posted in BCI Spotlight Articles, Images, In the Press, Publications Published by Zoe Leech 23 June 2016

Newly discovered cell signalling platform could enable metastasis

Cancer cells

A key question in cancer research has been how cancer cells are able to survive once they break away from a tumour to spread around the body.

This publication from the Kermorgant lab showing a previously unknown signalling pathway from integrin beta-1 and c-Met could be key to cancer cell survival in metastasis...

London Pancreas Workshop 2016

Posted in BCI Spotlight Articles, Events Published by Katrin Hood 10 May 2016

London Pancreas Workshop 2016

Professors Hemant Kocher and Nick Lemoine co-organised the sixth biennial London Pancreas Workshop, which took place on Friday 29th April. The conference is billed as a forum for state-of-the-art clinical and basic research in pancreatic cancer.

The event was a huge success, bringing together medics, students, charities, and sponsors. 150 delegates were in attendance, packing out the lecture theatre. 

Making anti-cancer viruses safer for ovarian cancer patients

Posted in Publications Published by Zoe Leech 24 June 2015

Making anti-cancer viruses safer for ovarian cancer patients

Dr Michelle Lockley's group has published a new study in Cancer Research showing exciting progress in the use of viruses to treat ovarian cancer.

They've found a way to potentially reduce inflammation by targeting an integrin on macrophage cells, which oncolytic viruses can bind to...

Prizes awarded to BCI Haemato-Oncology researchers

Posted in Grants & Awards, Publications Published by Zoe Leech 06 March 2015

Prizes awarded to BCI Haemato-Oncology researchers

Two prizes of note have been awarded to Haemato-oncology clinicians: Dr John Riches has been awarded the Hamblin Prize For the best published paper in chronic lymphocytic leukaemia (CLL) last year. Dr Shamzah Araf has been awarded free sample sequencing to support his lymphoma project...

Promising antibody against cancer cells characterised at BCI to be developed for clinical trials

Posted in General News Published by Zoe Leech 21 January 2015

Exciting bench-to-bedside news from our Centre for Tumour Biology!

We can confirm that a new drug that has been characterised and tested in the laboratory of our Professor John Marshall will be used in upcoming clinical trials.

The antibody 264RAD that targets integrin αvβ6 will be tested in patients for the first time...

NCRI Conference 2014 Review

Posted in Conferences, BCI on the Road Published by Marianne Baker 12 November 2014

NCRI Conference 2014 Review

BCI staff and researchers attended this year's NCRI conference in Liverpool last week, where we showcased our research at our exhibitor's stand.

Two of our senior researchers spoke in symposia on the tumour microenvironment and cancer model systems and 12 PhD students and post-docs presented posters...

Bone Marrow FAK effect on cancer spreading discovered

Posted in Publications Published by Zoe Leech 08 October 2014

Bone Marrow FAK effect on cancer spreading discovered

Nature Communications has published Sílvia Batista's findings on what happens to cancer spreading (metastasis) when a protein called FAK is missing from the bone marrow. Another part of this puzzle revealed by the Hodivala-Dilke lab...

Extra chromosome in CLL encourages cancer cells' evasive action

Posted in Publications Published by Zoe Leech 30 May 2014

Extra chromosome in CLL encourages cancer cells' evasive action

A new paper from the Centre for Haemato-Oncology has been published in the journal Blood. The lead author is Dr John Riches, a clinical post-doctoral researcher in the laboratory of the Centre Lead, Professor John Gribben.

Dr Riches and colleagues investigated a form of blood cancer called chronic lymphocytic leukaemia (CLL), with specific genetic characteristics...

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