Articles tagged with: Microenvironment

BCI at the 59th ASH Annual Meeting

Posted in General News, Conferences, BCI on the Road Published by Reza Roozitalab 08 December 2017

"The most prestigious event in the haematology calendar"

BCI at the 59th ASH Annual Meeting

Research teams from our Centre for Haemato-Oncology have once again joined the world’s most influential figures in haematology to present their cutting-edge findings at the 59th ASH Annual Meeting & Exposition.

Study sheds new light on how cancer cells adapt to become aggressive

Posted in General News, Publications Published by Reza Roozitalab 04 December 2017

Centrosome amplification: not as clear cut as once thought

Study sheds new light on how cancer cells adapt to become aggressive

A new study from Dr Susana Godinho’s lab has revealed surprising insights into how cancer cells adapt to ‘centrosome amplification’ – a mechanism that they have previously demonstrated to be essential in allowing certain tumours to become aggressive and metastatic.

Hugh Brasher and Pancreatic Cancer UK Visit the BCI

Posted in General News, Engagement Published by Reza Roozitalab 10 November 2017

November is Pancreatic Cancer Awareness Month #PCAM

Hugh Brasher and Pancreatic Cancer UK Visit the BCI

Hugh Brasher and members of the team from Pancreatic Cancer UK visited the BCI to learn about the latest research and what is being done to beat pancreatic cancer sooner.

Cancer cells "talking to themselves" could be key to cancer spreading

Posted in BCI Spotlight Articles, Images, In the Press, Publications Published by Zoe Leech 23 June 2016

Newly discovered cell signalling platform could enable metastasis

Cancer cells

A key question in cancer research has been how cancer cells are able to survive once they break away from a tumour to spread around the body.

This publication from the Kermorgant lab showing a previously unknown signalling pathway from integrin beta-1 and c-Met could be key to cancer cell survival in metastasis...

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Posted in In the Press, Publications Published by Zoe Leech 15 June 2016

New study published in Clinical Cancer Research by Prof Balkwill

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Professor Fran Balkwill has published a study on ovarian cancer responses to treatment, which could mean hope for patients whose cancer has already spread.

The findings suggest that giving chemotherapy before surgery could improve tumour responses to immunotherapy given afterwards, by making the cancer cells more susceptible to immune attack by the immune system...

Dr Susana Godinho awarded the prestigious Lister Prize – a first for QMUL

Posted in Grants & Awards Published by Zoe Leech 01 June 2016

Dr Susana Godinho awarded the prestigious Lister Prize – a first for QMUL

Dr Susana Godinho in our Centre for Molecular Oncology has become the first lecturer at BCI - and Queen Mary University of London as a whole - to be awarded the prestigious Lister Prize Fellowship.

Just five excellent researchers receive this award each year...

Vitamin A could boost pancreatic cancer chemotherapy

Posted in In the Press, Publications Published by Zoe Leech 25 May 2016

Vitamin A could boost pancreatic cancer chemotherapy

The latest study from the Kocher lab, published recently in the Journal of Pathology, has found that adding high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer.

This finding is now being taken forward in the clinical trial, STARPAC, by our Centre for Experimental Cancer Medicine.

BCI success in Academy of Medical Sciences grant awards

Posted in Grants & Awards Published by Zoe Leech 13 May 2016

BCI success in Academy of Medical Sciences grant awards

Three researchers from Queen Mary University of London (QMUL) have been awarded £100,000 each by the Academy of Medical Sciences. Two are here at BCI: Dr Paulo Ribeiro and Dr Angus Cameron.

The grants are designed to support researchers in the first years of their independent career with funds, training and mentoring. Angus' grant is for the study of cancer-associated fibroblasts (CAFs) while Paulo’s grant will fund a project studying tissue growth mechanisms...

Funding secured to revolutionise personalised prostate cancer treatments

Posted in Grants & Awards Published by Zoe Leech 23 November 2015

3D tumour model to test anti-cancer viruses & drugs

Funding secured to revolutionise personalised prostate cancer treatments

Barts Charity have funded a new project led by Dr Gunnel Halldén in our Centre for Molecular Oncology. This work aims to develop a method to test new combinations of cancer treatments on prostate cancer.

Ultimately they hope to use the test for individual patients, to provide personalised therapies...

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Posted in Publications Published by Zoe Leech 14 July 2015

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Two new papers from our Centre for Haemato-Oncology in the journal Blood show that boosting the immune system could help control Chronic Lymphocytic Leukaemia (CLL).

The studies focus on two proteins called “Programmed Death Ligand 1” (PD-L1) and Programmed Death 1” (PD-1), found on the surface of tumour and immune cells respectively...

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