BCI Group Leaders

Professors, Clinical & Non-clinical Senior Lecturers, Readers and Lecturers at BCI


  • Professor Nick Lemoine

    Director of Barts Cancer Institute. Primary research interests in the genomics and molecular pathology of pancreatic cancer and the development of oncolytic virotherapy.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Alexandra Aicher

    I work on CAR T-cell therapies for pancreatic cancer

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Katiuscia Bianchi

    I work on cancer cell evasion of cell death, how cancer cell metabolism affects tumour growth and how inflammation can drive malignant transformation.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Andrejs Braun

    I work on antibody therapies for lymphoma and the epigenetics of somatic hypermutation in normal and malignant B cells

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Angus James Cameron

    Protein kinases represent the largest group of drug targets in cancer therapy. My research focuses on kinases regulating cancer cell growth and motility to understand how and when to target them with drugs.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Esther Castellano-Sanchez

    My work is on the role of oncogenic Ras signalling in cancer development and the interplay between tumour cells and the microenvironment in lung and pancreatic cancer.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Claude Chelala

    My research interests lie in the area of computational and integrative bioinformatics. Current research projects are focused in next-generation sequencing/array data analysis/integration, databases and software development. 

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Tatjana Crnogorac-Jurcevic

    We study molecular pathology of cancer development and progression and are developing urine biomarkers for early, non-invasive detection of pancreatic cancer.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Pedro Cutillas

    We use unique proteomics and computational approaches to understand signalling heterogeneity in cancer and advance personalized cancer therapies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Jeff Davies

    My clinical and research interests are allogeneic haematopoietic stem cell transplantation; graft-versus-host disease/graft-versus-tumour effects; and adoptive immunotherapy.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Gabriella Ficz

    My group is interested in how normal cells turn into cancer cells and what role aberrant epigenetic alterations and reprogramming events play in this process

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Jude Fitzgibbon

    My group works on haematological malignancy molecular pathology and progression, aiming to improving on current diagnostic, prognostic and treatment strategies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Susana Godinho

    Our research group focuses on understanding how centrosome amplification impacts tumour progression and how we can target this to develop new cancer therapies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Trevor Graham

    My lab measures the patterns of clonal evolution that define carcinogenesis and develops novel mathematical tools for analysis and prediction.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Richard Grose

    We are interested in how cancer cells signal to each other and to their surrounding cells, and how this knowledge can be exploited to develop novel targeted therapies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Gunnel Halldén

    My main research interest is in the development of novel treatment strategiesfor prostate and pancreatic cancers using oncolytic virotherapy.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Kairbaan Hodivala-Dilke

    We study the molecular basis of how the stroma contributes to tumour growth and spread, particularly tumour angiogenesis in various solid tumours.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Zuzana Horejsi

    My lab focuses on discovering functions of phosphorylation induced by damaged DNA in normal and cancer cells, and on investigating the role of different phosphorylation events in cancer development.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Li Jia

    My group focuses on the inflammatory microenvironment, disease progression and resistance to treatment in haematological malignancies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Louise Jones

    My research in breast cancer focuses on the progression of in-situ to invasive disease with the aims of identifying markers which can predict behaviour and novel therapeutic targets.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Stéphanie Kermorgant

    My main research interest is in the role of growth factor receptor signalling and trafficking in tumour metastasis.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Hemant Kocher

    I am a surgeon-scientist with clinical and translational research interests in pancreatic cancer stroma and tumour-stroma cross-talk

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Sergey Krysov

    My main research interests are in the biology of B-cells and in the development of B-cell malignancies, particularly the B-cell receptor.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Rifca Le Dieu

    I am interested in understanding how cancer cells ‘switch off’ the normal immune response in acute myeloid leukaemia with the aim of developing novel immunotherapeutic strategies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Irene Leigh

    My research has centred on all aspects of keratinocyte biology from studying basic epithelial differentiation into disease applications, particularly the molecular mechanisms of skin cancer, genetic disease and tissue engineering.

  • Dr Michelle Lockley

    I am a clinician scientist investigating ovarian cancer, specifically oncolytic viral therapies and the host immune response to these agents, as well as new therapies for treatment-resistant cancers.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Daniela Loessner

    I am a cell biologist using interdisciplinary approaches to develop 3D models that mimic the human disease in the laboratory in order to find better therapeutics.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Yong-Jie Lu

    We aim to identify genomic alterations and genetic risk factors that influence the development, progression and therapeutic responses of male urogenital tumours, in particular prostate cancer.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Ranjit Manchanda

    My research is on ovarian and endometrial cancer population risk, screening, genetics and prevention techniques including surgical methods.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Faraz Mardakheh

    My lab studies how synthesis of cellular proteins is spatially and temporally dysregulated in cancer cells, and how this dysregulation contributes to cancer progression.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor John F Marshall

    I study the role of adhesion molecules - particularly integrins - in the development and spread of cancer, as well as their potential applications in imaging and therapy

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Sarah Martin

    Our research is based on exploiting DNA repair defects in cancer for the identification of new personalised therapies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Sarah McClelland

    We are interested in understanding the mechanisms controlling genomic stability, and how these are deregulated in cancer.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Stuart McDonald

    Our research focuses on stem cell niches and clonal expansion in Barrett's oesophagus, stomach and breast cancer.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Jessica Okosun

    My research focuses on understanding the genetic and molecular mechanisms that underlie the initiation and progression of B-cell non-Hodgkin's lymphomas in order to define clinically-relevant biomarkers.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Mr Bijendra Patel

    I am a Clinical Senior Lecturer in Upper Gastrointestinal Surgery and Course Director for the Surgical Skills and Sciences MSc at BCI.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Oliver M Pearce

    The focus of our research is the tumour microenvironment (TME). We are particularly interested in understanding the composition and function of the tumour extracellular matrix in immunosuppression.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Thomas Powles

    My main research interests are in genital and urinary cancers, leading a spectrum of clinical studies from phase I to randomised phase III.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr David Propper

    I am lead for GI trials with a focus on pancreatic cancer. I work with scientists within the BCI in crosscutting themes targeting the tumour microenvironment. These approaches include...

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Prabhakar Rajan

    My research focuses on RNA modification in prostate cancer (PCa), as well as translational work and clinical epidemiology.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Paulo Ribeiro

    Our research group uses the fruit fly Drosophila melanogaster to uncover the molecular mechanisms regulating tissue growth, invasion and metastasis, in particular ubiquitylation.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr John Riches

     My major research interest is understanding the immunobiology and metabolism of chronic lymphocytic leukaemia with the aim that this will underpin the development of the next generation of therapeutic agents for this disease.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Kevin Rouault-Pierre

    My main research interests are in haematopoietic stem cells (HSCs) and leukemic initiating cells. I seek to understand how intrinsic and extrinsic signals are integrated by normal and malignant stem cells.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Shah-Jalal Sarker

    My biostatistical research focuses on design, implementation and analysis of cancer clinical trials, cost-effectiveness trials, sample sizing, survival analysis, frailty modelling and missing data methods.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Jane Sosabowski

    My main interests are in radiopharmaceutical development and the use of pre-clinical molecular imaging in drug development, especially biopharmaceuticals.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Peter Szlosarek

    My main research interest is in exploring why argininosuccinate synthetase (ASS1), a rate-limiting enzyme in L-arginine synthesis, is aberrantly expressed in human cancers and how this knowledge may be exploited for anticancer therapy.

    I lead an active translational programme from bench to bedside of the arginine-depleting agent ADI-PEG20 in several hard-to-treat cancers including ADAM, TRAP and ATOMIC clinical studies.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Professor Yaohe Wang

    We work on cancer prevention, diagnosis and treatment using tumour-targeted oncolytic viruses, in particular focusing on personalised cancer vaccines and viro-immunotherapy.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Jun Wang

    My main research interests are: discovery of driver mutations and pathways in cancer development & progression, and in clonal evolutionary patterns using bioinformatics & computational approaches.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Ping Pui Wong

    My research focuses on understanding the molecular basis of chemoresistance in breast cancer treatment

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
  • Dr Bela Wrench

    My research focuses on the fundamental aspects of leukaemia initiating cell biology in adult acute lymphoblastic leukaemia.

    • This email address is being protected from spambots. You need JavaScript enabled to view it.
This site uses cookies in order to function properly. By continuing to browse, you agree that we can save them on your device. Privacy Policy.