Module Details

Details of all the Institute’s postgraduate taught modules are given below. Please refer to the individual programme content for a list of modules that feature on a particular programme.

All 15 and 7.5 credit modules are available to be studied as individual modules for non-award bearing learning.

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Research Methods (15 Credits)

Semester: 1

Module Leader: Professor John F Marshall

The module contains both taught and practical elements in which students learn about the principles and application of data analysis, a range of statistical methods, and are made aware of the ethical framework in which research is undertaken.

Assessment: 50% coursework 50% exam

Research Lab Skills (15 Credits)

Semester: 1

Module Leader: Professor John F Marshall

The module contains both taught and practical elements in which students learn about the principles and applications of a range of laboratory techniques and gain experience in handling tissue samples.

Assessment: 50% coursework 50% exam

Cancer Biology (15 Credits)

Taught: Semester 1

Module Leader: Dr Richard Grose & Dr Andrejs Ivanov

This module covers cell and molecular biology relevant to cancer, including:

  • Basic cellular and molecular biology
  • Key proteins and pathways regulating cell proliferation and cell death
  • The processes of carcinogenesis and DNA damage
  • The key cellular and molecular processes affected in tumour development
  • A broader concept of malignancy and its environment processes involved in invasion and metastasis

Assessment: 40% coursework 60% exam

Cancer Pharmacology (15 Credits)

Taught: Semester 1

Module Leader: Dr Richard Grose & Dr Jane Sosabowski

This module will provide teaching in Pharmacology relevant to the treatment of malignant disease, including:

  • The basic concepts of cancer chemotherapy
  • Practical and theoretical aspects of pharmacokinetics and pharmacodynamics
  • The basic clinical and molecular pharmacology of the major classes of anticancer agents
  • Novel cancer therapies using small molecules.

Assessment: 40% coursework 60% exam

Basic Pathology (15 Credits)

Taught: Semester 1

Module Leader: Professor Louise Jones

This module will provide an understanding of cellular and clinical aspects of cancer pathology, focussing mainly on the histological features of neoplastic processes in common tumours. By the end of the module students will have a good understanding of;

  • Normal tissue histology
  • Tumour histology
  • The classification and staging of tumours
  • The effects of tumours on normal pathology

Assessment: 40% coursework 60% exam

Pathology of Cancer (7.5 Credits)

Taught: Semester 1

Module Leader: Professor Louise Jones

This module will provide an understanding of cellular and clinical aspects of cancer pathology, focussing mainly on the histological features of neoplastic processes in common tumours. By the end of the module students will have a good understanding of;

  • Normal tissue histology
  • Tumour histology
  • The classification and staging of tumours
  • The effects of tumours on normal pathology

Assessment: 40% coursework 60% exam

Molecular Diagnostics & Therapeutics (15 Credits)

Taught: Semester 2

Module Leader: Dr Duncan Clark

This module will:

  • Provide an understanding of the principles and practice of molecular diagnosis in the detection and management of disease.
  • Provide an understanding of quality assurance issues in the diagnostic setting
  • Give examples of the use of current molecular techniques in the management of disease
  • Provide practical experience of molecular techniques

Assessment: 40% coursework 60% exam

Biological Therapies (15 Credits)

Taught: Semester 2

Module Leader: Dr Michelle Lockley

This module will provide an understanding of the science behind the biological therapies of cancer and an up-to-date review of the current status of preclinical and clinical trials. The module will also provide an insight into the ways that laboratory research is translated into clinical trials

Assessment: 40% coursework 60% exam

Molecular Pathology of Solid Tumours (15 Credits)

Taught: Semester 2

Module Leader: Professor Louise Jones

This course aims to provide students with detailed knowledge of the molecular mechanisms involved in cancer development and to give an appreciation of the current ‘hot topics’ in cancer research and their relevance to cancer diagnosis and management. The major topics to be covered are:

  • The molecular mechanisms involved in cancer development
  • The role of the microenvironment in cancer
  • Emerging changes in classification of cancers
  • Predisposition to cancer
  • Cancer stem cells

Assessment: 40% coursework 60% exam

Introduction to Bioinformatics (15 Credits)

Taught: Semester 2

Module Leader: Professor Claude Chelalala

Assessment: 40% coursework 60% exam

Molecular Targeted Therapies and Immunotherapy for Blood Cancers (15 Credits)

Taught: Semester 2

Module Leader: Dr Andrejs Ivanov

This module will cover the fundamental molecular and biological mechanisms involved in the development of leukaemia and lymphoma. It will specifically address the impact of chromosome abnormalities on the diagnosis, prognosis, risk stratification and management of patients and include a theoretical and practical understanding of cytogenetic and molecular cytogenetic technology. The contribution of the host microenvironment to tumour cell survival and proliferation will also be discussed.

Assessment: 40% coursework 60% exam

Site Specific Tumour Treatment (7.5 Credits)

Taught: Semester 2

Module Leader: Dr Michelle Lockley

This module will provide students with an understanding of the basic principles and management of the major types of cancer, including:

  • Diagnosis and staging
  • Treatment
  • Prognosis
  • Late effects of treatment
  • Ongoing research and new developments

Assessment: 40% coursework 60% exam

Ablative Therapies (7.5 Credits)

Taught: Semester 2

Module Leader: Dr Sibtain Amen

This module will provide an understanding of the science and principles underlying the use of radiotherapy and surgery in the treatment of malignant disease.

Assessment: 40% coursework 60% exam

Drug Development (7.5 Credits)

Taught: Semester 2

Module Leader: Dr Gunnel Hallden

On completion of this module you will have detailed knowledge of the principles and practice of drug development at all stages of the development process. Topics covered include: 

  • Target identification
  • Compound library screening with hit to lead optimisation
  • Pharmacokinetics/pharmacodynamics and current model systems
  • All phases of clinical trials focussing on regulations, ethical and good practice issues
  • Trial data analysis including median survival, determination of hazard ratios and Cox scores

Assessment: 40% coursework 60% exam

Imaging (7.5 Credits)

Taught: Semester 1

Module Leader: Dr Jane Sosabowski

This module will provide an understanding of the science and principles underlying the use of a number of imaging modalities in the diagnosis and treatment of malignant disease. The use of imaging in preclinical cancer research will also be covered

Assessment: 40% coursework 60% exam

Paediatric & Adolescent Oncology (7.5 Credits)

Taught: Semester 2

Module Leader: Dr Tony Ford

The module will provide an intense and comprehensive overview of Paediatric Oncology, from disease aetiology to novel treatments, and aims to equip the student with a fundamental understanding of the subject area. Topics covered include:

  • The aetiology of paediatric leukaemia and selected paediatric solid tumours
  • The molecular aspects of selected paediatric cancers, and how understanding the genetic basis of such cancers has improved molecular diagnostic techniques
  • The principles of paediatric cancer therapy, from past to present, including novel targeted therapies
  • The treatment of malignant disease in adolescence

Assessment: 40% coursework 60% exam

Cancer Prevention & Screening (7.5 Credits)

Taught: Semester 2

Module Leader: Professor Peter Sasieni

This module will provide an understanding of population based studies and methodology used in cancer epidemiology, focusing on the value of these approaches in cancer prevention and in the design and evaluation of screening programmes. Topics covered include:

  • The major environmental causes of cancer and their contribution to cancer worldwide
  • The potential for reducing cancer incidence
  • The role of screening in cancer control
  • The prospects for the chemoprevention of cancer in the next 10 years

Assessment: 40% coursework 60% exam

Genomic Approaches to Cancer (7.5 Credits)

Taught: Semester 2

Module Leader: Dr Tatjana Crnogorac-Jurcevic

This module will provide detailed teaching on the principles, interpretation and applications of large scale ‘omics’ approaches to cancer, including:

  • working principles of different platforms for studying genome, epigenome, transcriptome, proteome and metabolome,
  • critical assessment of the advantages and limitations of ‘omics’ approaches
  • the application of ‘omics’ technologies in personalised medicine

Assessment: 40% coursework 60% exam

Lab Project (60 Credits)

Taught: Semester 3

Onsite students will select from a range of project titles. Full-time students will be expected to attend 5 days a week. For part-time students, arrangements will be made on a case by case basis, dependent on individual circumstances.

Assessment: 100% coursework

Dissertation(60 Credits)

Taught: Semester 3

Students will select from a range of dissertation titles. A supervisor will be assigned to support you in your research.

Assessment: 100% coursework

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