Barts Cancer Institute - Queen Mary University of London

Thursday Seminar Series - Abigail Coetzee
2019-10-24 12:30 - 13:30 (Europe/London) | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Abigail Coetzee to present at the BCI on Thursday 24th October. For more information about Abigail Coetzee’s research please click here.
The seminar is entitled: ‘Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer’.
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.

Thursday Seminar Series: Professor Conrad Bessant
2019-10-17 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Professor Conrad Bessant from QMUL’s School of Biological and Chemical sciences to present at the BCI on Thursday 17th October. For more information about Professor Bessant’s work click here.
The seminar is entitled: ‘Leveraging Proteomics Data for Cancer Research’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.

Special Seminar: Dr Angelo Agathanggelou
2019-10-10 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Angelo Agathanggelou from the Institute for Cancer and Genomic Sciences, University of Birmingham to present at the BCI on Thursday 10th October. For more information about Dr Angelo Agathanggelou’s research please click here.
The seminar is entitled: ‘Targeting the RNaseH2-defect in human malignancies’

Special Seminar: Dr Mirjana Efremova
2019-10-09 17:00 - 18:00 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to announce that Dr Mirjana Efremova from the Wellcome Sanger Institute will present at the BCI on Wednesday 9th October.
Mirjana did her BSc (Computer Science) and MSc (Bioinformatics) in Macedonia. She then completed her PhD in the field of computational cancer immunology at the Medical University of Innsbruck. Mirjana is interested in the role of the immune system in cancer progression. At the Teichmann Lab, she is applying single cell technologies and computational approaches to study the cellular diversity within the tumour microenvironment and to understand the underlaying mechanisms involved in mediating interactions between tumour and immune cells.
The seminar is entitled: “Decoding cell-cell communication networks by single cell transcriptomics”
The seminar will be held in the Lister and Young Seminar Room, 15:00-16:00.

Thursday Seminar Series - Dr Paolo Baptista-Ribeiro
2019-10-03 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to announce that Dr Paulo Baptista-Ribeiro will present at the BCI on Thursday 3rd October. For more information about Dr Ribeiro’s research please click here.
The seminar is entitled: “Role of protein post-translational modifications in the regulation of tissue growth”
The seminar will be held in the Lister and Young Seminar Room, 12.30 – 13.30.

CRUK Centre for Drug Development Seminar
2019-09-26 09:30 - 10:45 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
Meet the Centre for Drug Development (CDD) at CRUK Barts Centre on 26th September to learn about the support they offer to help translate your research into the clinic.
The session will include:

An overview of the translation capabilities and support available from the CDD
Group discussions on how to tackle challenges in translating academic research
The opportunity to ask questions and talk to CDD colleagues and experts about your projects and ideas.

Date & time: Thursday 26 September | 09:30 –10:45
Location: Lister & Young Seminar Room | 2nd Floor John Vane Science Centre
If you are interested in attending, please register on the Eventbrite page.

Thursday Seminar Series – Dr Amaya Viros
2019-09-19 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Amaya Viros from the University of Manchester to present at the BCI on Thursday 19th September. For more information about Dr Amaya Viros please click here.
The seminar is entitled: ‘Melanoma in the elderly population.’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.

Thursday Seminar Series - Prof Jude Fitzgibbon
2019-09-12 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Professor Jude Fitzgibbon from BCI to present on Thursday 12th September. For more information about Prof Fitzgibbon’s research, please click here.
The seminar is titled: ‘Leukaemia and Lymphoma research: it starts with a patient’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Prof Fitzgibbon, please contact him directly on j.fitzgibbon@qmul.ac.uk.

Special Seminar - Prof. Erwei Song
2019-08-05 13:00 - 14:00 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Professor Erwei Song from the Sun Yat-sen University (SYSU) to present a Special Seminar at the BCI on Monday 5th August. For more information about Prof. Song’s research, please click here.
The seminar will be titled: ‘Treat the cancer soil: Turn foes to friends’
The seminar will be held in the Lister and Young Seminar Room, 1– 2pm.
If you would like to arrange to talk with Prof. Song, please contact Emily Marsh (e.marsh@qmul.ac.uk).
Abstract: Current paradigms of cancer-centric therapeutics are usually not sufficient to eradicate the malignancy, while cancer stroma may prompt tumor relapse and therapeutic resistance. Among all the stromal cells that populate the tumor microenvironment, tumor-associated macrophages (TAMs), cancer-associated fibroblasts (CAFs) and tumor-infiltrated lymphocytes (TILs) are the most abundant and are critically involved in cancer progression. Tumor stromal cells regulate the biology of tumor cells via cell-cell contact, numerous regulatory factors and synthesizing or remodeling the extracellular matrix, and thus affect cancer initiation and development. Therefore, recent characterization of tumor microenvironment brings stroma-targeting therapies for cancer treatment onto the agenda. In our studies, we not only underscore the contribution of tumor stroma components to cancer progression, but also highlight the relevant translational advances and potential therapeutic strategies that target tumor soil for cancer treatment.

Special Seminar - Prof. Jeffrey Pollard
2019-07-25 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Professor Jeffrey Pollard from the MRC Centre for Reproductive Health, University of Edinburgh, to present a Special Seminar at the BCI on Thursday 25th July. For more information about Prof. Pollard’s research, please click here.
The seminar will be titled: ‘Macrophages: Bad Actors in Cancer’
The seminar will be held in the Lister and Young Seminar Room, 12.30 – 1.30pm.
If you would like to arrange to talk with Prof. Pollard, please contact Nicholas Summerfield (n.summerfield@qmul.ac.uk).

Special Seminar - Prof. Aidan Doherty
2019-07-18 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Professor Aidan Doherty from the University of Sussex to present a Special Seminar at the BCI on Thursday 18th July. For more information about Prof. Doherty’s research, please click here.
The seminar will be titled: ‘Uncovering PrimPol’s roles in the maintenance of DNA replication & genome stability in vertebrate cells’
Please click here to see the seminar abstract.
The seminar will be held in the Lister and Young Seminar Room, 12.30 – 1.30pm.
If you would like to arrange to talk with Prof. Doherty, please contact Sarah McClelland (s.mcclelland@qmul.ac.uk).

Special Seminar - Dr Luigi Ombrato
2019-07-11 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Dr Luigi Ombrato from The Crick to present a Special Seminar at the BCI on Thursday 11th July. For more information about Dr Ombrato’s research, please click here.
The seminar will be titled: ‘A new in vivo labelling system reveals stem-like parenchymal cells in the lung metastatic niche’
The seminar will be held in the Lister and Young Seminar Room, 12.30 – 1.30pm.
If you would like to arrange to talk with Dr Ombrato, please contact Nicholas Summerfield (n.summerfield@qmul.ac.uk).

Distinguished Guest Lecture - Professor Robert Bristow
2019-06-20 16:00 - 17:00 | Derek Willoughby Lecture Theatre, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, United Kingdom
We are delighted to welcome Professor Robert Bristow from The University of Manchester to present his Distinguished Guest Lecture on Thursday 20th June. Further information on Professor Bristow’s research can be found here.
The lecture is titled: Harnessing Cancer Metabolism to Prevent Genetic Instability: The Hypoxia Story
The lecture will take place in the Derek Willoughby Lecture Theatre, 16:00-17:00.
If you would like to meet with Professor Bristow prior to his lecture, please contact Emily Marsh (e.marsh@qmul.ac.uk) to arrange a meeting.

Thursday Seminar Series - Dr. Vivian Li
2019-06-20 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr. Vivian Li from the Crick to present at the BCI on on 20th June. For more information about Dr. Li’s research, please click here.
The seminar is titled: “Wnt signal regulation in stem cell and cancer”
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr. Li, please contact Gabi Ficz (g.ficz@qmul.ac.uk).
Vivian Li obtained her PhD at the University of Hong Kong in 2008, characterising human colonic development and tumourigenesis. She then received the Croucher Foundation Fellowship to pursue her post-doctoral training in Hans Clevers’ lab at the Hubrecht Institute (the Netherlands), where she studied Wnt regulatory mechanisms in the intestine. Vivian Li is now a group leader at the Francis Crick Institute. Her lab investigates signalling regulation of intestinal stem cell and cancer, with primary focus on Wnt signalling pathways. She has recently been awarded the 2018 Future Leaders in Cancer Research Prize by CRUK for her contribution to bowel cancer research.

Thursday Seminar Series - Dr Pierre Guermonprez
2019-06-13 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Pierre Guermonprez, from King’s College London, to present at the BCI on Thursday 13th June. For more information about Dr Guermonprez’s research, please click here.
The seminar is titled: ‘Dendritic cells and tumour immunity’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr Guermonprez, please contact Kairbaan Hodivala-Dilke (k.hodivala-dilke@qmul.ac.uk).

Thursday Seminar Series - Professor Angus Lamond
2019-06-06 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Professor Angus Lamond from the University of Dundee to present at the BCI on Thursday 6th June. For more information about Prof Lamond’s research, please click here and see document attached.
The seminar is titled: ‘Deep Proteomes, iPS cells & Data Mountains’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Prof Lamond, please contact Emily Marsh (e.marsh@qmul.ac.uk).
Abstract:
Deep mining of proteomes, using mass spectrometry (MS) based proteomics technology, can provide invaluable insights, at a systems level, into both physiological responses in healthy cells and mechanisms causing disease phenotypes. This allows unbiased, global, quantitative measurements linking cellular phenotypes with changes in protein dynamics in both healthy and diseased cells. Furthermore, beyond identifying protein abundance, proteomics technology can now also provide a flexible suite of quantitative assays that can be used to characterize a multi-dimensional array of ‘Protein Properties’ that affect cell phenotypes. This includes, for example, subcellular protein localization, turnover rates, posttranslational modifications, cell cycle variation and specific protein complexes and proteinprotein interactions etc. A major challenge that now emerges from this ability to generate very large sets of proteomics data is how to manage, analyse and integrate the huge resulting volumes of complex information. I will describe a recent project where we have used quantitative proteomics for large-scale studies of human induced pluripotent stem cells (iPSCs), involving the analysis of over 200 iPSC lines derived from both healthy donors and patient cohorts with specific inherited disorders. This project highlights some of the technical and analytical challenges inherent in performing proteomic analyses at this scale. I will also describe user-friendly, computational tools we have built for the effective management and sharing of these large, multidimensional data sets (see; www.peptracker.com/epd).

Thursday Seminar Series - Prof Malcolm Clench
2019-05-30 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Professor Malcolm Clench from Sheffield Hallam University to present at the BCI on Thursday 30th May. For more information about Prof Clench’s research, please click here.
The seminar is titled: ‘Mass Spectrometry Imaging of 3D Tissue Models’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Prof Clench, please contact Andrejs Braun (andrejs.braun@qmul.ac.uk).

Thursday Seminar Series - Dr Chris Tape
2019-05-23 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Chris Tape from UCL to present at the BCI on Thursday 23rd May. For more information about Dr Tape’s research, please click here.
The seminar is titled: ‘Single-Cell Signalling Analysis of Tumour Micro-environment Organoids’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr Tape, please contact Faraz Mardakheh (f.mardakheh@qmul.ac.uk).

Thursday Seminar Series - Prof Tim Elliott
2019-05-09 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Professor Tim Elliott from the University of Southampton to present at the BCI on Thursday 9th May. For more information about Prof. Elliott’s research, please click here.
The seminar is titled: ‘Peptide selection in the MHC I antigen processing pathway and its relevance to cancer’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.

Special Seminar – Bjorn Bakker
2019-05-03 16:00 - 17:00 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Bjorn Bakker, from the European Research Institute for the Biology of Aging (Netherlands), to present a Special Seminar at the BCI on Friday 3rd May. For more information about Bjorn Bakker’s research, please click here.
The seminar will be titled: ‘Karyotype evolution in Chromosomal Instability-driven cancer’
The seminar will be held in the Lister and Young Seminar Room, 4 – 5pm.
If you would like to arrange to talk with Bjorn Bakker, please contact Sarah McClelland (s.mcclelland@qmul.ac.uk).

CRUK City of London Centre Workshop
2019-04-29 13:00 - 17:00 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We would like to invite you to the CRUK City of London (CoL) Centre 3D in vitro models for pre-clinical studies of biological therapies workshop.
This informal workshop will present and discuss in vitro models that could be used to study novel biological therapies and their combination. Presentations will include 3D multi-cellular models of tumour microenvironments, tumour organoids, the potential of microfluidics and tumour-on-a-chip, immune cell interactions with tumour spheroids. We will discuss about collaborations and needs for common platforms in the CRUK CoL Centre and key questions that such models could answer.
The workshop will take place in the Lister Young Seminar Room from 13.00 to 17.00, with refreshments and informal networking afterwards. All are welcome!
View the full programme here
To book a space please RSVP before the 17th April 2019 to cruk.cityoflondoncentre@ucl.ac.uk.

Special Seminar - Dominik Glodzik
2019-04-01 10:30 - 11:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
We are pleased to welcome Dr Dominik Glodzik from the Wellcome Sanger Institute to present a Special Seminar at the BCI on Monday 1st April. For more information about Dr Glodzik’s research please click here.
The seminar is titled: ‘Causes and consequences of DNA repair defects revealed from whole genome sequences of cancers’
The seminar will be held in the Lister and Young Seminar Room, 10.30am – 11.30am.
If you would like to arrange to talk with Dr Glodzik, please contact Jude Fitzgibbon (j.fitzgibbon@qmul.ac.uk).

Thursday Seminar Series - Dr Barrie Peck
2019-03-28 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Barrie Peck from The Institute of Cancer Research to present at the BCI on Thursday 28th March. For more information about Dr Peck’s research, please read the biography below.
The seminar will be titled: ‘Modelling the tumour microenvironment to identify novel targets in cancer’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr Peck, please contact Denise Gardner (d.gardner@qmul.ac.uk).

Biography:
Doctor Barrie Peck studied Molecular Biology and Genetics at Royal Holloway before moving to Imperial College London to complete a PhD in studying the role and regulation of forkhead transcription factors in breast cancer. After this, he moved to the London Research Institute (now the Crick Institute) to the lab of Prof. Almut Schulze to study cancer metabolism. This work focussed on identifying novel cancer-specific dependencies in cancer metabolism. Indeed, as part of the Lipid metabolism consortium, they identified ACSS2 as a fundamental dependency of aggressive breast and prostate cancers. There are now significant efforts in developing small molecule inhibitors to target ACSS2 in cancer.
Dr. Peck then moved to the Institute of Cancer Research to the lab of Dr. Rachael Natrajan to identify novel tumour suppressors in breast cancer. At the ICR he has developed bespoke 3-dimensional screening pipelines and discovered novel genes that impact disease progression and response to targeted therapies. This work was recently awarded a BCN Catalyst grant in collaboration with Pfizer.
Dr. Peck has a keen interest in functional genomics, cancer cell metabolism and the impact extrinsic factors, such as diet, can have on disease trajectory in cancer.

Thursday Seminar Series - Dr Kalnisha Naidoo
2019-03-21 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Kalnisha Naidoo from Guy’s and St Thomas’ to present at the BCI on Thursday 21st March.
The seminar will be titled: ‘Modelling Metastatic Spread to Human Lymph Nodes’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr Naidoo, please contact Emily Marsh (e.marsh@qmul.ac.uk).

Thursday Seminar Series - Dr Louisa James & Dr Hamish King
2019-03-14 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Louisa James and Dr Hamish King from The Blizard Institute to present at the BCI on Thursday 14th March. For more information about their research, please click here.
The seminar is titled: ‘Human B cell maturation at single-cell resolution’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr James and Dr King, please contact Hemant Kocher (h.kocher@qmul.ac.uk).

Thursday Seminar Series - Dr Alfredo Castello
2019-03-07 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Alfredo Castello from the University of Oxford to present at the BCI on Thursday 7th March. For more information about Dr Castello’s research please click here.
The seminar is titled: ‘RNA-binding proteins step into the host-virus battlefront’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr Castello, please contact Faraz Mardakheh (f.mardakheh@qmul.ac.uk).

Distinguished Guest Lecture - Professor Sir John Burn
2019-02-20 16:00 - 17:00 | G02, Joseph Rotblat Building, Barts Cancer Institute, Charterhouse Square, London, EC1M 6BQ
We are delighted to welcome Professor Sir John Burn from Newcastle University to present his Distinguished Guest Lecture on Wednesday 20th February, 16:00-17:00.
The lecture will be titled: “Getting Ahead of Cancer: Prediction and Prevention”
If you would like to meet with Professor Burn prior to his lecture, please contact Emily Marsh (e.marsh@qmul.ac.uk) to arrange a meeting.
Further information on Professor Burn’s research can be found here.

Exhibition - Gilson UK
2019-02-19 10:00 - 14:00 | John Vane Science Centre Foyer, Barts Cancer Institute, Charterhouse Square, London, EC1M 6BQ, United Kingdom
We are pleased to welcome Gilson UK for an Exhibition in the JVSC Foyer on Tuesday 19th February, 10am – 2pm.
Come along to:

See the range of liquid handling solutions
Get some goodies!
Speak to Gilson UK about pipette servicing offers
Try their new range of pipettes

For more information about the Exhibition, please click here: Exhibition poster- QMUL CH SQ

Thursday Seminar Series - 10x Genomics
2019-02-14 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcomeStephen Hague and James Hargreaves from 10x Genomics to present at the BCI on Thursday 14th February.
The seminar is titled: ‘10X Genomics, recent advances in Single Cell Genomics’
“The Chromium Single Cell Gene Expression Solution provides a comprehensive, scalable solution for cell characterization and gene expression profiling of hundreds to tens of thousands of cells. Our latest improvements allow you to detect even more unique transcripts per cell and with the addition of Feature Barcoding technology, you can get a more complete molecular readout cell by cell—identify cell-specific CRISPR-mediated perturbations or simultaneously measure gene and cell surface protein expression in the same cell, with virtually unlimited possibilities for the additional feature types.
Additionally, 10X Genomics provides solutions to measure Chromatin accessibility (ATAC), 5’ Gene expression, Single Cell immune profiling and Single Cell Copy number variation.
10X Genomics solutions have been used in over 400 peer reviewed publications. Please come along to our Seminar to find out more about this novel technology and recent advances.”
For more information about 10x Genomics, please click here.
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Stephen or James, please contact Hemant Kocher (h.kocher@qmul.ac.uk).

Thursday Seminar Series - Dr Sarah McClelland
2019-02-07 12:30 - 13:30 | Lister and Young Seminar Room, John Vane Science Centre, London, EC1M 6BQ
As part of the BCI’s Seminar Series, we are pleased to welcome Dr Sarah McClelland from Barts Cancer Institute to present on Thursday 7th February. For more information about Dr McClelland’s research, please click here.
The seminar is titled: ‘Chromosomal instability through the cell cycle’
The seminar will be held in the Lister and Young Seminar Room, 12.30pm – 13.30pm.
If you would like to arrange to talk with Dr McClelland, please contact her via email: s.mcclelland@qmul.ac.uk.
