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MRC funding for research on cancer epigenetics at BCI

Posted in Grants & Awards Published by Zoe Leech 25 March 2015

MRC funding for research on cancer epigenetics at BCI

Dr Gabriela Ficz in the Centre for Haemato-Oncology will receive £860,000 to lead projects focused on understanding epigenetic changes in cancer's early stages.

Epigenetics is the modification of DNA in ways that do not change the code itself...

MRC grant funding success for BCI researchers

Posted in Grants & Awards Published by Zoe Leech 16 March 2015

MRC grant funding success for BCI researchers

Two new grants have been awarded to BCI researchers by the Medical Research Council (MRC).

Prof Hemant Kocher will now be able to run a Phase I trial for a new pancreatic cancer treatment, and Dr Yaohe Wang will be testing a modified cancer-killing (oncolytic) virus...

Prizes awarded to BCI Haemato-Oncology researchers

Posted in Grants & Awards, Publications Published by Zoe Leech 06 March 2015

Prizes awarded to BCI Haemato-Oncology researchers

Two prizes of note have been awarded to Haemato-oncology clinicians: Dr John Riches has been awarded the Hamblin Prize For the best published paper in chronic lymphocytic leukaemia (CLL) last year. Dr Shamzah Araf has been awarded free sample sequencing to support his lymphoma project...

New method to predict which pancreatic cancers are more aggressive

Posted in Publications Published by Zoe Leech 17 February 2015

New method to predict which pancreatic cancers are more aggressive

Dr Claude Chelala and her Bioinformatics group have tested a new way to classify and recommend treatment for pancreatic cancer patients. The results were published recently in Genome Medicine.

With further work to understand pancreatic cancer biology, the 36-gene signature they have described should provide opportunities to develop new drugs and methods to identify high-risk patients...

New "Big Bang" model of cancer growth in human colon

Posted in Publications Published by Zoe Leech 10 February 2015

New

Dr Trevor Graham has contributed to a new theory of how cancer grows in the human gut as part of a transatlantic collaboration - the findings were published yesterday in Nature Genetics.

This new "big bang" model of cancer initiation replaces a previous idea of how mutations in colon cells' DNA lead to cancer, and how they affect its growth and spread...

A new strategy to improve cancer treatment: Vascular Promotion Therapy

Posted in BCI Spotlight Articles, Publications Published by Zoe Leech 06 February 2015

A new strategy to improve cancer treatment: Vascular Promotion Therapy

A paper published in Cancer Cell recently from Professor Kairbaan Hodivala-Dilke’s laboratory could mark the beginning of a new strategy in cancer treatment.

The new tactics, tested in models of solid lung and pancreatic tumours, achieved four major goals: improved drug delivery to tumour cells; reduced tumour growth; decreased tumour spread (metastasis); and extended survival...

World Cancer Day 2015 - Barts Research supports new strategies

Posted in General News, Charity Published by Zoe Leech 04 February 2015

World Cancer Day 2015 - Barts Research supports new strategies

It's World Cancer Day: one in two people will develop cancer at some point in their lives, according to the most accurate forecast to date from the Barts CR-UK Centre for Cancer Prevention.

This increase from the previous estimate of 1 in 3 people highlights the need to improve public health and NHS cancer services so they can cope with a growing and ageing population...

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