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join us as we look back at some highlights of Barts Cancer Institute’s news stories of 2025.
Features 17 December 2025

Scientists have discovered that a single letter change in a gene called PRKCA drives a rare and hard-to-treat brain cancer, chordoid glioma, through an entirely unexpected mechanism. The findings could open up new ways to design targeted treatments for this difficult-to-treat disease, and possibly for other cancers involving the same gene.
General News 7 November 2025

Queen Mary University of London has launched a new company, Procyon Diagnostics, to provide pioneering early cancer detection tests. The company’s first test, PancRISK, offers new hope for detecting pancreatic cancer earlier, building on over 15 years of research by Professor Tatjana Crnogorac-Jurcevic at Queen Mary’s Barts Cancer Institute (BCI), funded by the Pancreatic Cancer Research Fund.
General News 29 October 2025

A new clinical trial led by Professor Thomas Powles at Barts Cancer Institute, Queen Mary University of London, has shown that a blood test to detect tumour DNA could help doctors decide which patients with bladder cancer are most likely to benefit from further treatment after surgery. The new approach improved survival in those identified as high-risk while safely sparing low-risk patients from unnecessary side effects.
Conferences 22 October 2025

Researchers have developed an artificial intelligence (AI) tool that could help doctors identify which skin cancers are most likely to spread. We spoke to Professor Jun (Alex) Wang, a group leader at BCI, and Dr Emilia Peleva, a Clinical Research Fellow and dermatologist in his team, about their new study, published in npj Precision Oncology.
General News 30 September 2025

An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively.
General News 8 September 2025

The new combination treatment offers hope to thousands of people living with advanced urothelial cancer. The clinical trials, led by Professor Tom Powles, showed that overall survival rates were almost twice as long with this new treatment compared to the current standard treatment.
General News 21 August 2025

The Pancreatic Cancer Research Fund Tissue Bank (PCRFTB) has become the first in England to receive ISO 20387:2018 accreditation, an international standard that recognises excellence in biobanking.
General News 19 August 2025

Researchers at Barts Cancer Institute (BCI), Queen Mary University of London, will play a part in a revolutionary new partnership with King’s College London and the University of Leeds, aiming to accelerate and optimise the clinical translation of healthcare nanotechnologies.
General News 11 August 2025

This month, we welcomed a total of 43 aspiring young scientists from across London to the Barts Cancer Institute (BCI), Queen Mary University of London, where they had the opportunity to meet researchers, try their hands in the lab and learn more about what it takes to become a scientist.
Engagement 29 July 2025

Molecules exhaled in the breath may provide clues to detect blood cancer, according to new research by scientists at Barts Cancer Institute. The findings could enable the development of a blood cancer breathalyser, providing a rapid, low-cost way to detect disease.
General News 23 July 2025

Researchers have discovered a new mechanism by which B cells – antibody-producing immune cells – use a cellular recycling process called autophagy to control changes to their DNA essential for antibody improvement. The findings could have future implications for the development of certain blood cancers and autoimmune diseases.
General News 2 July 2025

Scientists have uncovered how bowel cancer cells imitate our gut’s natural healing processes to adapt, spread and grow. The findings researchers at Barts Cancer Institute could lead to new treatment strategies aimed at preventing cancer spread.
General News 8 June 2025

A new strategy to help powerful cancer-targeting immune cells, known as CAR-T cells, infiltrate pancreatic tumours has been developed by researchers at Barts Cancer Institute, Queen Mary University of London.
General News 22 May 2025

Women of African or South Asian genetic ancestry tend to develop breast cancer and die at a younger age than women of European ancestry, according to new research by Barts Cancer Institute, Queen Mary University of London. The study, which looked at clinical and genetic data from over 7,000 women with breast cancer, also found important genetic differences in these women’s cancers that could impact their diagnosis and treatment.
General News 20 May 2025

Adaptive chemotherapy can prolong survival in lab models of ovarian cancer, according to new results. The findings could pave the way for a more effective and gentler approach to treating ovarian cancer that uses existing drugs in a more intelligent way.
General News 30 April 2025

Welcome to our newest group leader, Dr Alastair Lamb.
General News 3 April 2025

The Barts Cancer Institute (BCI), Queen Mary University of London, has been awarded the LEAF Bronze award for sustainability, achieving Bronze or Silver certification standards across each of our 15 laboratory sections.
General News 19 March 2025