Articles tagged with: Blood Cancers

Eliminating cancer stem cells: Scientists discover a novel drug target for aggressive blood cancer

Posted in General News, Publications Published by Bethan Warman 25 April 2019

Eliminating cancer stem cells: Scientists discover a novel drug target for aggressive blood cancer

Research published today in Cell Stem Cell has discovered a protein which drives an aggressive form of blood cancer, acute myeloid leukaemia (AML). Inactivation of this protein selectively compromises leukaemic cells while promoting normal blood cell functions.

BCI at the 60th ASH Annual Meeting

Posted in General News, BCI on the Road Published by Bethan Warman 14 January 2019

‘The premier event in malignant and non-malignant haematology’

BCI at the 60th ASH Annual Meeting

Researchers from our Centre for Haemato-Oncology attended the 60th American Society of Hematology (ASH) Annual Meeting and Exposition, which took place in San Diego on 1st-4th December 2018. The ASH Annual Meeting provides an invaluable opportunity to showcase the work being conducted here at the BCI and brings together professionals from all subspecialties of blood disease research.

BCI welcomes two new Group Leaders

Posted in General News Published by Bethan Warman 07 November 2018

BCI welcomes two new Group Leaders

We are pleased to welcome two new members of academic staff to the BCI- Professor Victoria Sanz-Moreno, joining us from King’s College, London, and Professor Kamil R Kranc, joining us from the University of Edinburgh.

Accelerator Award to improve early detection and intervention of blood cancers

Posted in General News, Grants & Awards Published by Bethan Warman 09 October 2018

Accelerator Award to improve early detection and intervention of blood cancers

BCI researchers are lead members of an international team to be funded by an Accelerator Award, which will bring together scientists from the UK, Spain and Italy in a bid to improve early detection and intervention of blood cancers. The award of £4.8M over 5 years, funded through a partnership between Cancer Research UK (CRUK), AIRC and FC AECC, encourages cross-institutional collaboration to unite resources and expertise to accelerate progress in cancer research.

Blood Cancer Awareness Month 2018

Posted in General News Published by Bethan Warman 28 September 2018

Blood Cancer Awareness Month 2018

Blood Cancer Awareness Month takes place every September to raise awareness of the challenges faced by those living with blood cancer. In the UK, blood cancer is the fifth most common cancer, with 240,000 people living with the disease and 38,000 people being diagnosed with a type of blood cancer each year. The three main blood cancer types are leukaemia, lymphoma and myeloma; however, there are over 100 individual types.

CRUK Gibraltar Committee visit the BCI

Posted in General News, Engagement Published by Bethan Warman 18 July 2018

CRUK Gibraltar Committee visit the BCI

We were recently visited by two members of the CRUK Gibraltar Committee, Giovi and Deborah, who came to the BCI for a laboratory tour with Dr Ana Rio-Machin, a postdoctoral researcher in the Centre for Haemato-Oncology. Ana’s research focuses on leukaemia, a type of blood cancer in which patients present an abnormal growth of white blood cells.

Following an introduction to the work that is conducted here to help better understand and treat leukaemia, provided by Ana’s supervisor, Prof Jude Fitzgibbon, Giovi and Deborah visited the laboratories to see where this research takes place.

Follicular lymphoma marked by spatial tumour heterogeneity

Posted in General News, Publications Published by Bethan Warman 23 March 2018

A challenge for targeted therapy

Follicular lymphoma marked by spatial tumour heterogeneity

A research team at the BCI, Queen Mary University of London, led by Dr Jessica Okosun, Centre for Haemato-Oncology, has found that tumours at different sites within the same patient with follicular lymphoma can be genetically diverse. This suggests that a sole biopsy is incapable of capturing all the genetic events in any given individual and presents a significant challenge when providing targeted therapies to treat this disease.

Follicular lymphoma is an incurable blood cancer that is characterised by the production of abnormal B lymphocytes (a type of white blood cell involved in fighting infection) that accumulate primarily in the lymph nodes and bone marrow. Approximately 2,300 cases of follicular lymphoma are diagnosed in the UK each year.

Some leukaemia patients may be missing out on new treatments

Posted in General News, Publications Published by Bethan Warman 11 January 2018

Some leukaemia patients may be missing out on new treatments

Patients with an aggressive form of leukaemia, currently ineligible for any type of targeted therapy, may in fact benefit from new drugs, according to new research by Barts Cancer Institute at Queen Mary University of London.

One such drug, named midostaurin, was recently approved by the US Food and Drug Administration to treat this type of leukaemia, but only patients who show mutations on a gene named FLT3 are eligible for treatment.

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