In this Centre, we employ unbiased high-throughput sequencing, mass spectrometry and multispectral imaging of tumour samples to gain unique insights into cancer evolution, genetics and cell signalling through from premalignancy to metastatic disease. Our ambition is to see translation of new knowledge into improvements in early cancer detection and precision medicine.
In the Centre for Cancer Evolution, we employ unbiased high-throughput sequencing, mass spectrometry and multispectral imaging of tumour samples to gain unique insights into cancer evolution, genetics and cell signalling through from premalignancy to metastatic disease.
We are internationally recognised for our work on lymphoma, leukaemia and gastrointestinal cancers, and the creation of computational tools to extract maximum value from Big Data.
Our ambition is to see translation of new knowledge into improvements in early cancer detection and precision medicine.
Centre Lead
Deputy Centre Lead
John Vane Science Centre,
Charterhouse Square,
London EC1M 6BQ
Professor of Cancer Genomics
Senior Lecturer
Clinical Reader in Prostate Cancer Evolution
Clinical Professor of Medical Oncology, Honorary Consultant
Professor of Cancer Cell Biology and Genomics
Professor of Gastrointestinal Biology
Professor in Genomics and Data Science
Reader in Somatic Evolution
Researchers have uncovered a mechanism that makes some cancer cells especially vulnerable to experimental drugs known as ATR inhibitors. The findings could support the development of tests to identify the patients most likely to benefit.
Publications 17 August 2026
Researchers have developed a new way to understand how genetic changes linked to blood cancer evolve in our cells, offering new insight into predicting blood cancer risk.
Publications 5 May 2026
