Our group investigates cancer evolution, with a focus on understanding how genetic changes influence disease progression, response to therapy and development of resistance. We particularly concentrate on gastrointestinal cancers such as colorectal, stomach and oesophageal cancer.
In my research, I examine the response of immune cells to different chemotherapy drugs in order to develop more effective cancer immunotherapy combinations. I use patient-derived organoids (from oesophageal cancer patients), 3D models, T cell co-culture models, flow cytometry, IHC(-F, H&E) and ELISA.