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Dr Roberto Bellelli
Senior Lecturer

My lab aims to understand the basic mechanisms controlling DNA replication in mammalian cells and how disruption of this process leads to genomic instability and cancer.

Dr Kevin Rouault-Pierre
Reader in Stem Cell Biology and Disease

My main research interests are in haematopoietic stem cells (HSCs) and leukemic initiating cells. I seek to understand how intrinsic and extrinsic signals are integrated by normal and malignant stem cells.

Dr Amanda Jimenez-Pompa

I am interested in unveiling and modelling the mechanisms that drive clonal haematopoiesis and exploring niche-based therapies to prevent it, as clonal haematopoiesis has been recently linked to an increase in the development of leukaemia and cardiovascular conditions.

Dr Christopher Mapperley

My research is focused on investigating how the epitranscriptome regulates normal and malignant haematopoiesis.

Dr Raul Sanchez Lanzas

Our research is focused in defining the cellular interactome of haematopoietic stem cells and leukaemic stem cells inside their niches during adulthood, ageing and disease. We are also interested in the cellular and molecular mechanisms that drive clonal selection and evolution in clonal haematopoiesis.

Dr Mike Williams

My research focusses on understanding cancer-specific metabolism in acute myeloid leukaemia and targeting this metabolism to overcome therapeutic resistance. I also explore the role of diet and obesity in leukaemogenesis and response to therapy.