My research focuses on elucidating the mechanisms underlying cancer cell invasion. In particular, I’m interested in the role of plasma membrane dynamics in mediating cancer cell interaction with its immediate environment, notably by allowing cancer cells to remodel and cleave the extracellular matrix, thus leading to cell breakage into the surrounding environment.
My research focuses on the development of radiopharmaceuticals for imaging and therapy of cancer, and translating these to the clinic
My research in Prof Balkwill’s group focuses on imaging tumour-associated macrophages and other immune cells in live ex vivo tumour slices, in order to assess their behaviour and the impact of immunotherapies on the live tumour microenvironment.
Our research focuses on the principles of spatial biology, integrating digital pathology, multi-omic data, and various imaging modalities to explore tissue architecture and the tumour microenvironment.
My research focuses on implementing and developing novel radioisotopes for targeted alpha therapy and improving stability and pharmacokinetics of radiolabelled peptides.
My research uses microscopy to examine how microtubule post-translational modifications affect DNA damage repair and how this could be exploited to enhance chemotherapy.