Overview
My research lies at the intersection of mathematics and biology, incorporating computer simulations, statistics, large-scale data analysis and image processing to study the evolution of cancer, and in particular the impact of early cancer evolution on tumourigenesis, the development of intratumour heterogeneity, and treatment response. My current research focusses on deciphering the role of extrachromosomal DNA in driving cancer progression, oncogene amplification and treatment resistance.
Related News

Rogue’ DNA rings reveal earliest clues to deadly brain cancer’s growth
An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively.
General News 8 September 2025

Researchers shed light on the mystery of liver cells’ origins
Understanding how new liver cells are created could inform how and why cell growth spirals out of control in cancer
General News 30 May 2023
