Cancer Type: Acute Myeloid Leukaemia
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Dr Mike Williams
8th August 2024
My research focusses on understanding cancer-specific metabolism in acute myeloid leukaemia and targeting this metabolism to overcome therapeutic resistance. I also explore the role of diet and obesity in leukaemogenesis and response to therapy.
Read moreDr Megha Meena
7th August 2024
We use novel mass cytometry technology following allogeneic haematopoietic stem-cell transplantation in patients, to define the global landscape of immune-cell populations preceding development of acute graft-versus-host disease (aGvHD) and to identify a dominant immunoregulatory role for subsets of CD56hi NK cells in limiting alloreative T-cell expansion and aGvHD.
Read moreDr Sandra M. Martin-Guerrero
7th August 2024
My work is focused on exploiting cell cycle vulnerabilities in tumour cells, particularly the role of MASTL or Greatwall kinase in cell cycle control. My research will explore the role of MASTL in AML and whether it could be a new therapeutic target in this disease.
Read moreDr Arantxa Carrasco Leon
7th August 2024
My research project aims to identify germline mutations in acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) and to understand their contribution in the development of these haematological diseases, using in vitro and ex vivo models. This study will lead to a step forward in the diagnosis and treatment of this group of life-threatening diseases.
Read moreDr James Boncan
26th January 2023
My research investigates the functional relevance of RNA-binding proteins (RBPS) in normal haematopoiesis and acute myeloid leukaemia (AML) pathogenesis.
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