Cancer Type: Prostate
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Dr Max Beesley
10th April 2025
My research focuses on improving our understanding of why only certain prostate cancer clones within a patient (intratumoural) undergo metastasis. I will apply next-generation spatial transcriptomics to investigate clonal evolution, identify key driver mutations and better understand clonal interaction with the stromal tumour microenvironment (TME).
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Dr Alastair Lamb
10th February 2025
Our lab focusses on Spatial Prostate Assessment and the Circulating Environment (aka the SPACE Group). We use cutting edge spatial molecular techniques to unpack clonal dynamics in the development of localised prostate cancer. Alongside this we seek to identify scalable “windows” into clonal lethality using machine learning approaches applied to histology and MRI images as well as ‘liquid biopsy’ of circulating tumour cells (CTCs). Our aim is to transform decision-making in clinical management of prostate cancer so that the right men get the right treatment at the right time.
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Dr Rachel Lawrence
10th October 2022
My research focuses on measuring circulating tumour cells as a blood-based biomarker for aggressive prostate cancer.
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Professor Daniel M Berney
9th September 2021
My focus is on the pathology and natural history of prostate, testicular and penile cancer working to translate basic research into practical treatments for patients with novel tests and bespoke predictive treatments.
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Dr Helen Ross-Adams
11th October 2018
The aim of my work is to develop clinically-relevant biomarkers that could aid in earlier disease detection, predict treatment response, and inform clinical management of patients.
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Professor Prabhakar Rajan
13th August 2018
My laboratory research explores alternative pre-mRNA splicing in prostate cancer (PCa) biology, and liquid biopsy-derived molecular biomarkers of treatment outcomes.
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