Staff Centre: Centre for Tumour Microenvironment
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Dr Beatrice Malacrida
17th February 2021
My research focuses on designing 3D in vitro models to understand the contribution of the tumour microenvironment during HGSOC progression.
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Dr Luigi Ombrato
24th March 2020
I lead the Metastatic Niche Lab, where we study how metastases form and what enables disseminated cancer cells to survive and grow in distant organs. Our research focuses on uncovering cell-cell interactions and signalling pathways within the tumour microenvironment that are critical for establishing a supportive metastatic niche. Our studies aim to identify key drivers of metastatic progression and new therapeutic targets to better prevent or treat metastatic cancers.
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Professor Victoria Sanz-Moreno
18th October 2018
Our research focuses on how the cytoskeleton of cancer cells regulates transcriptional rewiring during tumour growth and dissemination. We aim to understand how such rewiring affects the tumour microenvironment.
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Dr Florian Laforets
10th October 2018
My research in Prof Balkwill’s group focuses on imaging tumour-associated macrophages and other immune cells in live ex vivo tumour slices, in order to assess their behaviour and the impact of immunotherapies on the live tumour microenvironment.
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Dr David Propper
13th August 2018
My focus is on detailed translational trials in pancreatic cancer, with a focus on targeting the tumour microenvironment. Our aim is to define what perturbations occur in tumours of patients receiving trial drugs.
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Dr Oliver M. Pearce
13th August 2018
The focus of our research is the tumour microenvironment and we are particularly interested in understanding the composition and function of the tumour extracellular matrix in immunosuppression. Cancer types we focus on include ovarian and breast cancers.
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