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Dr Pedro Monteiro
Senior Lecturer
My research focuses on elucidating the mechanisms underlying cancer cell invasion. In particular, I’m interested in the role of plasma membrane dynamics in mediating cancer cell interaction with its immediate environment, notably by allowing cancer cells to remodel and cleave the extracellular matrix, thus leading to cell breakage into the surrounding environment.
Dr Malgorzata Maksymowicz-Trivedi
In my research, I study the effects of changed intracellular receptor trafficking on cellular signalling that leads to tumorigenicity and cancer metastasis. I also analyse the potential new interactions of cell signalling regulators.
Dr Lauryn Buckley-Benbow
My research investigates the mechanisms of sensitisation to PARP and ATR inhibitors and how dysfunction of normal DNA replication leads to genome instability and cancer.
Dr Tamsin Wilcock
My research focuses on developing novel methodology for in-cell monitoring of direct downstream kinase phosphorylation and phospho-isoform substrate specificity. This work will contribute towards enhancing our understanding of cell cycle protein signalling and elucidating the role of the activation loop in substrate switching.
Dr James Scarth
My research employs 3D tissue models of oncogenic HPV infection to study the contribution of oncogene-induced replication stress (Oi-RS) and genomic instability to cancer initiation.