Research Area: Cell Signalling
Filters
Research Areas
Centre
Position
Dr Malgorzata Maksymowicz-Trivedi
In my research, I study the effects of changed intracellular receptor trafficking on cellular signalling that leads to tumorigenicity and cancer metastasis. I also analyse the potential new interactions of cell signalling regulators.
Dr Tamsin Wilcock
My research focuses on developing novel methodology for in-cell monitoring of direct downstream kinase phosphorylation and phospho-isoform substrate specificity. This work will contribute towards enhancing our understanding of cell cycle protein signalling and elucidating the role of the activation loop in substrate switching.
Dr Sandra M. Martin-Guerrero
My work is focused on exploiting cell cycle vulnerabilities in tumour cells, particularly the role of MASTL or Greatwall kinase in cell cycle control. My research will explore the role of MASTL in AML and whether it could be a new therapeutic target in this disease.
Dr Daniele Di Biagio
Daniele Di Biagio is a Postdoctoral Researcher at Barts Cancer Institute, Queen Mary University of London.
Dr Arantxa Carrasco Leon
My research project aims to identify germline mutations in acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) and to understand their contribution in the development of these haematological diseases, using in vitro and ex vivo models. This study will lead to a step forward in the diagnosis and treatment of this group of life-threatening diseases.
Dr Irina Titkova
My research focuses on exploiting cell cycle vulnerabilities and signalling rewiring in tumour cells, to find new approaches to treat cancer.