Research Area: Cell Signalling

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Dr Marta Crespi-Sallan

My research is focused on describing the mechanisms underlying Lamin B1 nuclear disassembly in B-cell normal development and how a dis-regulated Lamin B1 removal pathway could lead to several haematological malignancies within the germinal centre in secondary lymph organs.

Dr Kunal Shah

I am studying how the tumour suppressor gene LIMD1 functions in the microRNA pathway, a gene regulatory pathway that is often dysregulated in cancer.

Dr Pedro Casado-Izquierdo

My work is based on studying signalling networks in AML primary samples in order to predict responses to kinase inhibitors.

Dr Kevin Rouault-Pierre
Reader in Stem Cell Biology and Disease

My main research interests are in haematopoietic stem cells (HSCs) and leukemic initiating cells. I seek to understand how intrinsic and extrinsic signals are integrated by normal and malignant stem cells.

Dr John Riches
Clinical Reader in Cancer Immuno-metabolism

My major research interest is understanding the metabolism of chronic lymphocytic leukaemia and lymphoma with the aim that this will underpin the development of the next generation of anti-metabolic drugs for these diseases.

Dr Paulo Ribeiro
Reader in Cell and Developmental Biology

Our research group is interested in uncovering the molecular mechanisms regulating tissue growth, invasion and metastasis using the fruit fly Drosophila melanogaster as a genetically tractable model organism.