Research Area: Metastasis and Invasion

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Centre for Tumour Biology(6)
Centre for Tumour Microenvironment(5)
Centre for Cancer Evolution(3)
Centre for Cancer Biomarkers and Biotherapeutics(2)
Centre for Cancer Cell and Molecular Biology(2)
Centre for Experimental Cancer Medicine(1)
Position
Dr Pedro Monteiro
Senior Lecturer

My research focuses on elucidating the mechanisms underlying cancer cell invasion. In particular, I’m interested in the role of plasma membrane dynamics in mediating cancer cell interaction with its immediate environment, notably by allowing cancer cells to remodel and cleave the extracellular matrix, thus leading to cell breakage into the surrounding environment.

Dr Alastair Lamb
Senior Clinical Lecturer, Barts Cancer Institute Visiting Associate Professor, Oxford University Honorary Consultant Urological Surgeon, Guy's and St Thomas'​ NHS Foundation Trust

Our lab focusses on Spatial Prostate Assessment and the Circulating Environment (aka the SPACE Group). We use cutting edge spatial molecular techniques to unpack clonal dynamics in the development of localised prostate cancer. Alongside this we seek to identify scalable “windows” into clonal lethality using machine learning approaches applied to histology and MRI images as well as ‘liquid biopsy’ of circulating tumour cells (CTCs). Our aim is to transform decision-making in clinical management of prostate cancer so that the right men get the right treatment at the right time.

Dr Daniele Di Biagio

Daniele Di Biagio is a Postdoctoral Researcher at Barts Cancer Institute, Queen Mary University of London.

Dr Rachel Lawrence

My research focuses on measuring circulating tumour cells as a blood-based biomarker for aggressive prostate cancer.

Dr Juan Manuel Marti

My current project dissects the role that the protein FAK plays on the induction of senescence observed in endothelial cells (ECs) after DNA damage therapy, and its role in lung cancer metastasis.

Dr Sam Ogden

We are using single cell multi-omic approaches to study how cancer cell plasticity and the tumour microenvironment contribute to metastasis in colorectal cancer.