Research Area: Metastasis and Invasion

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Centre for Tumour Biology(6)
Centre for Tumour Microenvironment(5)
Centre for Cancer Evolution(3)
Centre for Cancer Biomarkers and Biotherapeutics(2)
Centre for Cancer Cell and Molecular Biology(2)
Centre for Experimental Cancer Medicine(1)
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Dr Panoraia Kotantaki

My research is focused on the tumour microenvironment of ovarian cancer with a particular focus on the extracellular matrix and how current and novel treatments influence this microenvironment.
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Dr Mirjana Efremova
Senior Lecturer

We are interested in understanding the cellular and molecular mechanisms that promote cancer cell plasticity and adaptation of tumour cells in metastatic niches and under therapeutic pressure.
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Dr Luigi Ombrato
Senior Lecturer

I lead the Metastatic Niche Lab, where we study how metastases form and what enables disseminated cancer cells to survive and grow in distant organs. Our research focuses on uncovering cell-cell interactions and signalling pathways within the tumour microenvironment that are critical for establishing a supportive metastatic niche. Our studies aim to identify key drivers of metastatic progression and new therapeutic targets to better prevent or treat metastatic cancers.
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Professor Victoria Sanz-Moreno
Honorary Professor of Cancer Cell Biology

Our research focuses on how the cytoskeleton of cancer cells regulates transcriptional rewiring during tumour growth and dissemination. We aim to understand how such rewiring affects the tumour microenvironment.

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Dr Louisa Chard

Our research focuses on the use of modified, replicating oncolytic Vaccinia viruses and adenoviruses armed with immune-modulatory genes such as cytokines to create a self-propagating treatment for tumours that results in long-term immunological memory to the tumour cells.
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Dr Paulo Ribeiro
Reader in Cell and Developmental Biology

Our research group is interested in uncovering the molecular mechanisms regulating tissue growth, invasion and metastasis using the fruit fly Drosophila melanogaster as a genetically tractable model organism.