Tag: Brain
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Discovery reveals new understanding of cancer-driving proteins in rare brain tumours and beyond
7th November 2025
Scientists have discovered that a single letter change in a gene called PRKCA drives a rare and hard-to-treat brain cancer, chordoid glioma, through an entirely unexpected mechanism. The findings could open up new ways to design targeted treatments for this difficult-to-treat disease, and possibly for other cancers involving the same gene.
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Blood test helps guide immunotherapy for bladder cancer
22nd October 2025
A new clinical trial led by Professor Thomas Powles at Barts Cancer Institute, Queen Mary University of London, has shown that a blood test to detect tumour DNA could help doctors decide which patients with bladder cancer are most likely to benefit from further treatment after surgery. The new approach improved survival in those identified as high-risk while safely sparing low-risk patients from unnecessary side effects.
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Rogue’ DNA rings reveal earliest clues to deadly brain cancer’s growth
8th September 2025
An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively.
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Cancer-killing virus treatment shows promise in brain tumour trial
8th November 2024
An innovative cancer-killing virus shows promise for tackling glioblastoma, an aggressive type of brain tumour, according to new results from a phase I clinical trial co-led by researchers at Barts Cancer Institute.
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