Tag: Pancreas
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Scientists explore new way to bring CAR-T cell therapy to pancreatic cancer
22nd May 2025
A new strategy to help powerful cancer-targeting immune cells, known as CAR-T cells, infiltrate pancreatic tumours has been developed by researchers at Barts Cancer Institute, Queen Mary University of London. The unique three-pronged approach could pave the way for making CAR-T cell therapy—a treatment that has transformed care for certain blood cancers—effective against pancreatic cancer, a disease that remains very difficult to treat.
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How non-cancerous cells in pancreatic cancer may weaken the immune system’s response
12th December 2024
New research sheds light on how certain non-cancerous cells in pancreatic cancer can affect the body’s natural immune defences and could have a significant impact on patients’ survival.
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Video: mini-tumours shed light on how pancreatic cancer spreads
19th December 2023
We spoke to Professor Richard Grose about his lab’s latest study, which uses mini-tumours to understand how pancreatic cancer coerces normal cells to help it spread to other tissues. The new paper has been featured on the cover of the latest issue of the Journal of Pathology.
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World Pancreatic Cancer Day: research reveals molecules that alter the disease’s spread
16th November 2023
‘Star-shaped’ cells in the pancreas emit molecules that alter the tumour’s aggressiveness
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New study suggests promising approach for treating pancreatic cancer
18th October 2023
Researchers have pinpointed the cells that drive the spread of pancreatic cancer and revealed a weakness in these cells that could be targeted using existing cancer drugs.
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Research identifies new way to halt pancreatic cancer invasion by targeting healthy cells
10th November 2022
Researchers from Barts Cancer Institute at Queen Mary University of London have identified a new channel of communication through which non-cancerous cells drive the invasion of cancer cells in pancreatic cancer. By blocking a particular signalling molecule within this pathway, called Fibroblast Growth Factor Receptor 1, the team was able to reduce invasion of pancreatic cancer cells in the laboratory.
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