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Cells’ recycling system plays a surprising role in shaping immune cells DNA

2nd July 2025

Researchers have discovered a new mechanism by which B cells – antibody-producing immune cells – use a cellular recycling process called autophagy to control changes to their DNA essential for antibody improvement. The findings could have future implications for the development of certain blood cancers and autoimmune diseases.

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Smarter chemotherapy approach could delay drug resistance in ovarian cancer

30th April 2025

Adaptive chemotherapy can prolong survival in lab models of ovarian cancer, according to new results. The findings could pave the way for a more effective and gentler approach to treating ovarian cancer that uses existing drugs in a more intelligent way.

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Scientists discover the ‘roadmap’ that aggressive cancer uses to spread around the body and identify ways to block its escape

14th February 2025

Scientists have discovered a new way to predict which tumours will become aggressive before they metastasise and spread around the body. The findings could help doctors spot which tumours are likely to be aggressive and cause metastatic cancer. They also open new avenues for treating cancer before it spreads.

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Protein level predicts immunotherapy response in bowel cancer

16th January 2025

Researchers have shown that the amount of a protein called CD74 can indicate which people with bowel cancer may respond best to immunotherapy.

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Discovery of lingering DNA damage could change our understanding of cancer development

15th January 2025

Dr Michael Spencer Chapman and team have uncovered forms of DNA damage in healthy cells that can persist unrepaired for years

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Surprising ‘two-faced’ cancer gene role supports paradigm shift in predicting disease

3rd January 2025

A genetic fault long believed to drive the development of oesophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer.

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