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Pancreatic cancer cells grown in culture, SEM. Anne Weston, Francis Crick Institute. Source: Wellcome Collection.
Scientists explore new way to bring CAR-T cell therapy to pancreatic cancer

22nd May 2025

A new strategy to help powerful cancer-targeting immune cells, known as CAR-T cells, infiltrate pancreatic tumours has been developed by researchers at Barts Cancer Institute, Queen Mary University of London. The unique three-pronged approach could pave the way for making CAR-T cell therapy—a treatment that has transformed care for certain blood cancers—effective against pancreatic cancer, a disease that remains very difficult to treat.

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Breast Cancer Inequalities: image shows two women in traditional South Asian and African dresses, with a pink breast cancer awareness ribbon
Beyond ‘one size fits all’: Study reveals ethnic differences in breast cancer development and outcomes, demanding tailored care approaches

20th May 2025

Women of African or South Asian genetic ancestry tend to develop breast cancer and die at a younger age than women of European ancestry, according to new research by Barts Cancer Institute, Queen Mary University of London. The study, which looked at clinical and genetic data from over 7,000 women with breast cancer, also found important genetic differences in these women’s cancers that could impact their diagnosis and treatment.

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Illustration of a blue cancer cell
Smarter chemotherapy approach could delay drug resistance in ovarian cancer

30th April 2025

Adaptive chemotherapy can prolong survival in lab models of ovarian cancer, according to new results. The findings could pave the way for a more effective and gentler approach to treating ovarian cancer that uses existing drugs in a more intelligent way.

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MRI brain scans of one of the trial participants who achieved a complete response. See original paper for more details. © Ning, W. et al. 2024 CC-BY 4.0
Cancer-killing virus treatment shows promise in brain tumour trial

8th November 2024

An innovative cancer-killing virus shows promise for tackling glioblastoma, an aggressive type of brain tumour, according to new results from a phase I clinical trial co-led by researchers at Barts Cancer Institute.

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International study reveals four distinct types of oesophageal cancer

23rd October 2024

New research reveals that the most common type of oesophageal cancer, oesophageal squamous cell carcinoma (ESCC), is composed of four distinct subtypes—each of which may benefit from different treatment approaches.

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Helping cancer patient advocates find their voice

10th October 2024

We recently welcomed a group of 16 cancer patient advocates into our labs for the 11th edition of our VOICE science for advocates course, co-run with the charity Independent Cancer Patients’ Voice.

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