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New AI model sheds light on high-risk skin cancer: Q&A with the authors
30th September 2025
Researchers have developed an artificial intelligence (AI) tool that could help doctors identify which skin cancers are most likely to spread. We spoke to Professor Jun (Alex) Wang, a group leader at BCI, and Dr Emilia Peleva, a Clinical Research Fellow and dermatologist in his team, about their new study, published in npj Precision Oncology.
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Rogue’ DNA rings reveal earliest clues to deadly brain cancer’s growth
8th September 2025
An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively.
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Could a breath test detect blood cancer?
23rd July 2025
Molecules exhaled in the breath may provide clues to detect blood cancer, according to new research by scientists at Barts Cancer Institute. The findings could enable the development of a blood cancer breathalyser, providing a rapid, low-cost way to detect disease.
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Cells’ recycling system plays a surprising role in shaping immune cells DNA
2nd July 2025
Researchers have discovered a new mechanism by which B cells – antibody-producing immune cells – use a cellular recycling process called autophagy to control changes to their DNA essential for antibody improvement. The findings could have future implications for the development of certain blood cancers and autoimmune diseases.
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Study reveals molecules enabling bowel cancer to hijack healing processes and spread
8th June 2025
Scientists have uncovered how bowel cancer cells imitate our gut’s natural healing processes to adapt, spread and grow. The findings researchers at Barts Cancer Institute could lead to new treatment strategies aimed at preventing cancer spread.
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Scientists explore new way to bring CAR-T cell therapy to pancreatic cancer
22nd May 2025
A new strategy to help powerful cancer-targeting immune cells, known as CAR-T cells, infiltrate pancreatic tumours has been developed by researchers at Barts Cancer Institute, Queen Mary University of London. The unique three-pronged approach could pave the way for making CAR-T cell therapy—a treatment that has transformed care for certain blood cancers—effective against pancreatic cancer, a disease that remains very difficult to treat.
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